Structural Characterization of Lecithin-Stabilized Tetracosane Lipid Nanoparticles. Part I: Emulsions

Schmiele M, Busch S, Morhenn H, Schindler T, Schmutzler T, Schweins R, Lindner P, Boesecke P, Westermann M, Steiniger F, Funari SS, Unruh T (2016)

Publication Status: Published

Publication Type: Journal article, Original article

Publication year: 2016

Journal

Journal of Physical Chemistry B American Chemical Society

Publisher: American Chemical Society

Book Volume: 120

Pages Range: 5505-5512

Journal Issue: 24

DOI: 10.1021/acs.jpcb.6b02519

Abstract

The structure of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC)-stabilized colloidal tetracosane emulsions was investigated by photon correlation spectroscopy and small-angle X-ray and neutron scattering, using emulsions with different neutron scattering contrasts. Special emphasis was placed on the structure of the DMPC stabilizer layer covering the emulsion droplets. A monolayer, structurally similar to a half DMPC bilayer, with a thickness of 16 å is found. Thereby, the phosphocholine headgroups arrange flat at the oil-water interface. A deep penetration of the tetracosane oil into the stabilizer layer can be ruled out.

Authors with CRIS profile

Martin Schmiele Professur für Nanomaterialcharakterisierung (Streumethoden) Torben Schindler Professur für Nanomaterialcharakterisierung (Streumethoden) Tilo Schmutzler Professur für Nanomaterialcharakterisierung (Streumethoden) Tobias Unruh Professur für Nanomaterialcharakterisierung (Streumethoden)

Additional Organisation(s)

Graduiertenkolleg 1896/2 In situ Mikroskopie mit Elektronen, Röntgenstrahlen und Rastersonden Exzellenz-Cluster Engineering of Advanced Materials (EAM) Interdisziplinäres Zentrum, Center for Nanoanalysis and Electron Microscopy (CENEM)

Involved external institutions

Universitätsklinikum Jena DE Germany (DE) Helmholtz-Zentrum Geesthacht Zentrum für Material- und Küstenforschung GmbH (HZG) DE Germany (DE) Institute Laue-Langevin (ILL) FR France (FR) European Synchrotron Radiation Facility (ESRF) FR France (FR) Technische Universität München (TUM) DE Germany (DE) Deutsches Elektronen-Synchrotron DESY DE Germany (DE)

How to cite

APA:

Schmiele, M., Busch, S., Morhenn, H., Schindler, T., Schmutzler, T., Schweins, R.,... Unruh, T. (2016). Structural Characterization of Lecithin-Stabilized Tetracosane Lipid Nanoparticles. Part I: Emulsions. Journal of Physical Chemistry B, 120(24), 5505-5512. https://doi.org/10.1021/acs.jpcb.6b02519

MLA:

Schmiele, Martin, et al. "Structural Characterization of Lecithin-Stabilized Tetracosane Lipid Nanoparticles. Part I: Emulsions." Journal of Physical Chemistry B 120.24 (2016): 5505-5512.

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