Macrophages in homeostatic immune function

Jantsch J, Binger KJ, Mueller DN, Titze J (2014)

Publication Type: Journal article

Publication year: 2014

Journal

Frontiers in Physiology Frontiers Media

Book Volume: 5

Pages Range: 146

DOI: 10.3389/fphys.2014.00146

Abstract

Macrophages are not only involved in inflammatory and anti-infective processes, but also play an important role in maintaining tissue homeostasis. In this review, we summarize recent evidence investigating the role of macrophages in controlling angiogenesis, metabolism as well as salt and water balance. Particularly, we summarize the importance of macrophage tonicity enhancer binding protein (TonEBP, also termed nuclear factor of activated T-cells 5 [NFAT5]) expression in the regulation of salt and water homeostasis. Further understanding of homeostatic macrophage function may lead to new therapeutic approaches to treat ischemia, hypertension and metabolic disorders.

Authors with CRIS profile

Jens Titze Department of Medicine 4 – Nephrology and Hypertension

Involved external institutions

Charité - Universitätsmedizin Berlin DE Germany (DE)

How to cite

APA:

Jantsch, J., Binger, K.J., Mueller, D.N., & Titze, J. (2014). Macrophages in homeostatic immune function. Frontiers in Physiology, 5, 146. https://doi.org/10.3389/fphys.2014.00146

MLA:

Jantsch, Jonathan, et al. "Macrophages in homeostatic immune function." Frontiers in Physiology 5 (2014): 146.

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