Biburger M, Nimmerjahn F (2012)
Publication Status: Published
Publication Type: Journal article, Report
Publication year: 2012
Publisher: Spektrum Akademischer Verlag GmbH
Book Volume: 18
Pages Range: 170-173
Journal Issue: 2
DOI: 10.1007/s12268-012-0161-4
Antibodies carry out effector functions either directly or by binding of immune complexes to cellular Fc-receptors. Here we focussed on two mouse models: a model for immune-thrombocytopenia, where platelets are depleted by injection of anti-platelet antibodies, and a model for lymphoma treatment, where B-cells are depleted by CD20-specific antibodies. In both cases we found the activating Fc-receptors FcγRI and IV to be essential for IgG activity. © Springer-Verlag 2012.
APA:
Biburger, M., & Nimmerjahn, F. (2012). Antibody effectors: Monocytes as mediators of immunoglobulin G-dependent effector functions. BioSpektrum, 18(2), 170-173. https://doi.org/10.1007/s12268-012-0161-4
MLA:
Biburger, Markus, and Falk Nimmerjahn. "Antibody effectors: Monocytes as mediators of immunoglobulin G-dependent effector functions." BioSpektrum 18.2 (2012): 170-173.
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