Biburger M, Berens C, Lederer T, Krec T, Hillen W (1998)
Publication Status: Published
Publication Type: Journal article, Original article
Publication year: 1998
Publisher: American Society for Microbiology
Book Volume: 180
Pages Range: 737-741
Journal Issue: 3
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0031935572&origin=inward
Eight Tn10 Tet repressor mutants with an induction-deficient phenotype and with primary mutations located at or close to the dimer interface were mutagenized and screened for inducibility in the presence of tetracycline. The second-site suppressors with wild-type-like operator binding activity that were obtained act, except for one, at a distance, suggesting that they contribute to conformational changes in the Tet repressor. Many of these long-range suppressors occur along the dimer interface, indicating that interactions between the monomers play an important role in Tet repressor induction.
APA:
Biburger, M., Berens, C., Lederer, T., Krec, T., & Hillen, W. (1998). Intragenic suppressors of induction-deficient tetR mutants: Localization and potential mechanism of action. Journal of Bacteriology, 180(3), 737-741.
MLA:
Biburger, Markus, et al. "Intragenic suppressors of induction-deficient tetR mutants: Localization and potential mechanism of action." Journal of Bacteriology 180.3 (1998): 737-741.
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