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Depth-encoded all-fiber swept source polarization sensitive OCT

Wang Z, Lee HC, Ahsen OO, Lee B, Choi W, Potsaid B, Liu J, Jayaraman V, Cable A, Kraus M, Liang K, Hornegger J, Fujimoto JG (2014)

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Publication Status: Published

Publication Type: Journal article

Publication year: 2014

Journal

Publisher: Optical Society of America

Book Volume: 5

Pages Range: 2931-2949

DOI: 10.1364/BOE.5.002931

Abstract

Polarization sensitive optical coherence tomography (PS-OCT) is a functional extension of conventional OCT and can assess depth-resolved tissue birefringence in addition to intensity. Most existing PS-OCT systems are relatively complex and their clinical translation remains difficult. We present a simple and robust all-fiber PS-OCT system based on swept source technology and polarization depth-encoding. Polarization multiplexing was achieved using a polarization maintaining fiber. Polarization sensitive signals were detected using fiber based polarization beam splitters and polarization controllers were used to remove the polarization ambiguity. A simplified post-processing algorithm was proposed for speckle noise reduction relaxing the demand for phase stability. We demonstrated systems design for both ophthalmic and catheter-based PS-OCT. For ophthalmic imaging, we used an optical clock frequency doubling method to extend the imaging range of a commercially available short cavity light source to improve polarization depth-encoding. For catheter based imaging, we demonstrated 200 kHz PS-OCT imaging using a MEMS-tunable vertical cavity surface emitting laser (VCSEL) and a high speed micromotor imaging catheter. The system was demonstrated in human retina, finger and lip imaging, as well as ex vivo swine esophagus and cardiovascular imaging. The all-fiber PS-OCT is easier to implement and maintain compared to previous PS-OCT systems and can be more easily translated to clinical applications due to its robust design. (C) 2014 Optical Society of America

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How to cite

APA:

Wang, Z., Lee, H.-C., Ahsen, O.O., Lee, B., Choi, W., Potsaid, B.,... Fujimoto, J.G. (2014). Depth-encoded all-fiber swept source polarization sensitive OCT. Biomedical Optics Express, 5, 2931-2949. https://doi.org/10.1364/BOE.5.002931

MLA:

Wang, Zhao, et al. "Depth-encoded all-fiber swept source polarization sensitive OCT." Biomedical Optics Express 5 (2014): 2931-2949.

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