Bioactive Glass Fiber-Reinforced PGS Matrix Composites for Cartilage Regeneration

Trevelin Souza M, Tansaz S, Dutra Zanotto E, Boccaccini AR (2017)


Publication Language: English

Publication Type: Journal article, Original article

Publication year: 2017

Journal

Book Volume: 10

Article Number: 83

Journal Issue: 1

DOI: 10.3390/ma10010083

Open Access Link: http://www.mdpi.com/journal/materials

Abstract

Poly(glycerol sebacate) (PGS) is an elastomeric polymer which is attracting increasing interest for biomedical applications, including cartilage regeneration. However, its limited mechanical properties and possible negative effects of its degradation byproducts restrict PGS for in vivo application. In this study, a novel PGS–bioactive glass fiber (F18)-reinforced composite was developed and characterized. PGS-based reinforced scaffolds were fabricated via salt leaching and characterized regarding their mechanical properties, degradation, and bioactivity in contact with simulated body fluid. Results indicated that the incorporation of silicate-based bioactive glass fibers could double the composite tensile strength, tailor the polymer degradability, and improve the scaffold bioactivity.

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How to cite

APA:

Trevelin Souza, M., Tansaz, S., Dutra Zanotto, E., & Boccaccini, A.R. (2017). Bioactive Glass Fiber-Reinforced PGS Matrix Composites for Cartilage Regeneration. Materials, 10(1). https://dx.doi.org/10.3390/ma10010083

MLA:

Trevelin Souza, Marina, et al. "Bioactive Glass Fiber-Reinforced PGS Matrix Composites for Cartilage Regeneration." Materials 10.1 (2017).

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