Occupational UV-Exposure is a Major Risk Factor for Basal Cell Carcinoma: Results of the Population-Based Case-Control Study FB-181

Schmitt J, Haufe E, Trautmann F, Schulze HJ, Elsner P, Drexler H, Bauer A, Letzel S, John SM, Fartasch M, Bruening T, Seidler A, Dugas-Breit S, Gina M, Weistenhöfer W, Bachmann K, Bruhn I, Lang BM, Bonness S, Allam JP, Grobe W, Stange T, Westerhausen S, Knuschke P, Wittlich M, Diepgen TL (2018)


Publication Type: Journal article

Publication year: 2018

Journal

Book Volume: 60

Pages Range: 36-43

Journal Issue: 1

DOI: 10.1097/JOM.0000000000001217

Abstract

The aim of this study was to investigate the role of occupational and nonoccupational ultraviolet (UV)-exposure concerning the development of basal cell carcinoma (BCC).We undertook a population-based multicenter case-control study. Patients with first incident BCC (n = 836) were propensity score matched by age and sex to controls without skin cancer (n = 836). Sociodemographic characteristics, clinical characteristics, and lifetime UV-exposure were assessed by trained investigators. The differential estimation of occupational and nonoccupational UV-exposure dosages was based on validated instruments and established reference values. Associations were assessed using multivariable-adjusted conditional logistic regression models.Individuals with high levels of occupational UV-exposure were at significantly increased BCC-risk compared with individuals with low [odds ratio (OR) 1.84; 95% confidence interval (95% CI) 1.19 to 2.83 and moderate (OR 1.97; 95% CI 1.20 to 3.22) occupational UV-exposure. Nonoccupational UV-exposure was not independently associated with BCC.Skin cancer prevention strategies should be expanded to the occupational setting.

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APA:

Schmitt, J., Haufe, E., Trautmann, F., Schulze, H.-J., Elsner, P., Drexler, H.,... Diepgen, T.L. (2018). Occupational UV-Exposure is a Major Risk Factor for Basal Cell Carcinoma: Results of the Population-Based Case-Control Study FB-181. Journal of Occupational and Environmental Medicine, 60(1), 36-43. https://dx.doi.org/10.1097/JOM.0000000000001217

MLA:

Schmitt, Jochen, et al. "Occupational UV-Exposure is a Major Risk Factor for Basal Cell Carcinoma: Results of the Population-Based Case-Control Study FB-181." Journal of Occupational and Environmental Medicine 60.1 (2018): 36-43.

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