A111: Macrophage plasticity and function during allergic inflammation of the lung
FAU own research funding: EFI / IZKF / EAM ...
Start date : 15.02.2026
End date : 15.08.2028
Project details
Scientific Abstract
Allergic asthma (AA) is an inflammatory lung disease. At present it is unclear how macrophage populations in the lung are altered at different stages of allergic inflammation (onset, acute phase, resolution). We will use a mouse AA model to address the population dynamics of macrophages using fate mapping mice, interrogate the role of IL-4/IL-13 and activating or inhibitory Fc receptors, and study the impact of macrophages on their tissue environment with mouse and human lung organoids.
