P178: Integrative analysis of single-cell RNA-seq data to unravel CAF subtypes in PDAC mouse models

FAU own research funding: EFI / IZKF / EAM ...


Start date : 01.02.2026

End date : 31.01.2027

Project details

Scientific Abstract

This project aims to develop a robust reference framework for CAF subtypes analysis by integrating scRNA-seq datasets from PDAC mouse models. By identifying consistent gene signatures, we will provide a foundation for studying CAF heterogeneity and their function in PDAC. The resulting dataset will enhance reproducibility in preclinical research and facilitate future studies of CAF dynamics in diverse tumor contexts.

Involved:

Renato Liguori Project Leader

Contributing FAU Organisations:

Department of Nephropathology Sonderforschungsbereich/Transregio 305/1 Über die Analyse der metastatischen Koloniebildung zu neuen systemischen Krebstherapien

Funding Source

Mittelgeber / Förderprogramme