KI-Rolle von EVs auf Darmentwicklung: Investigation of EVs’ protective role in developing intestine of zebrafish larvae

FAU own research funding: EFI / IZKF / EAM ...


Start date : 01.12.2025

End date : 30.11.2026


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Scientific Abstract

Extracellular vesicles (EVs) are membrane-bound nanoparticles essential for cell communication and organogenesis. We hypothesize that human breast milk-derived EVs (HBM-EVs) enhance intestinal maturation and regeneration. This study investigates HBM-EV protection in DSS-induced intestinal injury in zebrafish larvae, analyzing cell-morphology, inflammation, and tissue repair (Phalloidin, cleaved Caspase-3, TNF-?, Wnt5a), comparing EVs from three lactation stages.

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