P180: Investigation of the role of AP-1 transcription factors in melanoma dormancy in a 3D-printed model
FAU own research funding: EFI / IZKF / EAM ...
Start date : 15.09.2025
End date : 14.09.2026
Project details
Scientific Abstract
In this project, the role of the AP-1 transcription factors in tumor dormancy of malignant melanoma is investigated. Using our 3D biofabricated dormancy model, we could show that AP-1 factors are highly expressed in dormant melanoma cells. Additionally, preliminary data indicate an impact of AP-1 factors on the development of dormancy. To shed more light on the phenomenon of tumor dormancy, the role of AP-1 and respective signaling pathways will be analyzed in our 3D printed model system.
Involved:
Contributing FAU Organisations:
Lehrstuhl für Biochemie und Molekulare Medizin
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
