FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.09.2025
End date : 29.02.2028
This project aims at comprehensive human epitope-specific analyses of CD4 T cell responses in tonsils. Our central hypothesis is that CD4 T cell responses in human tonsils differ from those in peripheral blood in terms of immunodominant epitope specificities, phenotype, and TCR repertoire. Using single-cell RNA and TCR sequencing and peptide-HLA virus screens, we aim to deepen our understanding of CD4 T cell biology and create a valuable data resource for the scientific community.