A098: Deciphering autoreactive T cells and their receptors in rheumatoid arthritis
FAU own research funding: EFI / IZKF / EAM ...
Start date : 16.03.2023
End date : 15.09.2025
Project details
Scientific Abstract
Autoreactive T cells are thought to play a key role during the pathogenesis of rheumatoid arthritis (RA), but their specificity and their contribution to RA remain elusive. In this project, we will identify autoreactive T cells, their receptors and cognate antigens in RA patients, and study the dynamics of the autoreactive T cell response at different stages of RA. This will yield important information on the pathogenesis of RA and provide the base for a novel generation of immunotherapies.
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Institute of Microbiology – Clinical Microbiology, Immunology and Hygiene
Medizinische Fakultät
