A103: Role of secretory IgA molecules in the intestinal retro-transport mechanism and modulation of bacteria
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.07.2023
End date : 31.12.2025
Project details
Scientific Abstract
Intestinal diseases (IBD) are chronic inflammations of the gastrointestinal tract. Secretory antibodies (SIgA) are produced by mucosal surfaces and are intestinal defences. The project aims to elucidate the role of SIgA in the uptake/retro process at the endothelium. Furthermore, an analysis of the SIgA-selected bacterial strains in the intestine will be carried out and new targets for a SIgA-mediated therapeutic approach in therapy will be found.
Involved:
Benno Weigmann
Project Leader
Ralf Palmisano
Project Member
Stefan Wirtz
Project Member
Diana Dudziak
Project Member
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Department of Medicine 1 – Gastroenterology, Pneumology and Endocrinology
Professur für die Biologie Dendritischer Zellen
Medizinische Fakultät
FAU Optical Imaging Competence Center (FAU OICE)
