A094: Host cell factors and nonstructural proteins of SARS-CoV-2
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.07.2023
End date : 31.12.2025
Project details
Scientific Abstract
The continuous adaptation of the SARS-CoV-2 replicative machinery, as well as the consequences of nonstructural protein (Nsp) mutations to the virus-host interaction need to be considered in emerging variants. SARS-CoV-2 marker viruses will be used to address the role of existing and new variant virus mutations in Nsps in different culture systems, in viral replication and in their escape from cellular restriction, focusing on the non-spike related phenotype of these variants.
Involved:
Contributing FAU Organisations:
Professur für Stammzell-Modelle seltener neuraler Erkrankungen
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Institute of Clinical and Molecular Virology
Medizinische Fakultät
