P101: VATER/VACTERL association: exome analysis in human and functional studies in zebrafish
FAU own research funding: EFI / IZKF / EAM ...
Start date : 16.01.2022
End date : 15.01.2023
Extension date: 15.04.2023
Project details
Scientific Abstract
The VATER/VACTERL association describes the co-occurrence of malformations of the vertebral bodies, anorectum, heart, esophagus, kidneys, and limbs. The proposed study aims to identify new candidate genes and characterize the candidate gene FZD7 by morpholino knockdown and expression analysis in developing zebrafish larvae. In doing so, we hope to better understand the molecular mechanisms leading to this multisystem malformation.
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Professur für Neonatologie
Medizinische Fakultät
