IZKF-J63 (M1): The role of Interleukin-3 in experimental colitis and human inflammatory bowel disease
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.12.2017
End date : 30.11.2020
Project details
Scientific Abstract
The role of IL-3 in the pathogenesis of inflammatory bowel diseases (IBD) has not been explored so far. Preliminary data show that the course of oxazolone colitis is aggravated in IL-3 deficient mice vs. controls and that the expression of IL-3 is significantly increased in active ulcerative colitis. Therefore, this project is designed to address the role of IL-3 in experimental colitis and human IBD. This could lead to the identification of novel therapeutic targets for the treatment of IBD.
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Department of Medicine 1 – Gastroenterology, Pneumology and Endocrinology
Medizinische Fakultät
