Prof. Dr. med. Kilian Schober

Professur für T-Zell-Immunologie (Heisenberg-Professur) Medizinische Fakultät Institute of Microbiology – Clinical Microbiology, Immunology and Hygiene

LOWERING THE BINDING STRENGTH OF ANTI-CD19 CAR-T CELLS CAN REDUCE TOXICITY BUT AT THE COST OF IN VIVO ANTI-TUMOR EFFICACY (2022) Doetsch S, Warmuth L, D'Ippolito E, Honold B, Trebo M, Manlik W, Graml F, et al. Conference contribution DISSECTING THE INTERPLAY OF TCR AVIDITY OF NAIVE CD8+T CELLS AND TCR RECRUITMENT AFTER ANTIGEN EXPOSURE BY ENGINEERING POLYCLONAL REPERTOIRES (2022) Straub A, Grassmann S, Jarosch S, Muller T, Wagner K, Hammel M, Buchholz V, et al. Conference contribution GENE-TRANSFER METHODOLOGY AFFECTS CHIMERIC ANTIGEN RECEPTOR EXPRESSION AND REGULATION IN T-CELLS, AND DETERMINES ANTITUMOR POTENCY IN THE CONTEXT OF HIGH VS. LOW TARGET ANTIGEN DENSITY (2022) Gehrke L, Verbruggen C, Nerreter T, Schober K, Busch D, Einsele H, Sauer M, et al. Conference contribution ORTHOTOPIC T CELL RECEPTOR REPLACEMENT NEXT - GENERATION ENGINEERING OF T CELLS FOR THERAPY (2022) Schober K Conference contribution Orthotopic T-cell receptor replacement in primary human T cells using CRISPR-Cas9-mediated homology-directed repair. (2022) Moosmann C, Müller TR, Busch DH, Schober K Journal article Global k(off)-rates of polyclonal T-cell populations merge subclonal avidities and predict functionality (2022) Lueckemeier P, Molter KL, Jarosch S, Huppertz P, Purcarea A, Effenberger MJP, Nauerth M, et al. Journal article CMV seropositivity is a potential novel risk factor for severe COVID-19 in non-geriatric patients. (2022) Weber S, Kehl V, Erber J, Wagner KI, Jetzlsperger AM, Burrell T, Schober K, et al. Journal article T Cells Directed against the Metastatic Driver Chondromodulin-1 in Ewing Sarcoma: Comparative Engineering with CRISPR/Cas9 vs. Retroviral Gene Transfer for Adoptive Transfer. (2022) Xue B, von Heyking K, Gassmann H, Poorebrahim M, Thiede M, Schober K, Mautner J, et al. Journal article Protective T cell receptor identification for orthotopic reprogramming of immunity in refractory virus infections (2022) Stief TA, Kaeuferle T, Müller TR, Döring M, Jablonowski LM, Schober K, Feucht J, et al. Journal article, Original article Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through ‘reverse phenotyping’ (2021) Fischer DS, Ansari M, Wagner KI, Jarosch S, Huang Y, Mayr CH, Strunz M, et al. Journal article