Dr. med. Lucas Hoffmann

Institute of Neuropathology

Human brain tissue with MOGHE carrying somatic SLC35A2 variants reveal aberrant protein expression and protein loss in the white matter (2025) Cecchini E, Geffers S, Coras R, Schultheis D, Holtzhausen C, Karandasheva K, Herrmann H, et al. Journal article The Role of Perineuronal Nets in Physiology and Disease: Insights from Recent Studies (2025) Auer S, Schicht M, Hoffmann L, Budday S, Frischknecht R, Blümcke I, Paulsen F Journal article Analysis of 1386 epileptogenic brain lesions reveals association with DYRK1A and EGFR (2024) Boßelmann CM, Leu C, Brünger T, Hoffmann L, Baldassari S, Chipaux M, Coras R, et al. Journal article Age-dependent increase of perineuronal nets in the human hippocampus and precocious aging in epilepsy (2024) Lehner A, Hoffmann L, Rampp S, Coras R, Paulsen F, Frischknecht R, Hamer H, et al. Journal article, Original article Deep histopathology genotype–phenotype analysis of focal cortical dysplasia type II differentiates between the GATOR1-altered autophagocytic subtype IIa and MTOR-altered migration deficient subtype IIb (2023) Honke J, Hoffmann L, Coras R, Kobow K, Leu C, Pieper T, Hartlieb T, et al. Journal article Correction to: Ganglioglioma with adverse clinical outcome and atypical histopathological features were defined by alterations in PTPN11/KRAS/NF1 and other RAS-/MAP-Kinase pathway genes (Acta Neuropathologica, (2023), 10.1007/s00401-023-02561-5) (2023) Hoffmann L, Coras R, Kobow K, López-Rivera JA, Lal D, Leu C, Najm I, et al. Journal article, Erratum Ganglioglioma with adverse clinical outcome and atypical histopathological features were defined by alterations in PTPN11/KRAS/NF1 and other RAS-/MAP-Kinase pathway genes (2023) Hoffmann L, Coras R, Kobow K, López-Rivera JA, Lal D, Leu C, Najm I, et al. Journal article A deep learning-based histopathology classifier for Focal Cortical Dysplasia (2023) Vorndran J, Neuner C, Coras R, Hoffmann L, Geffers S, Honke J, Herms J, et al. Journal article The genomic landscape across 474 surgically accessible epileptogenic human brain lesions (2022) A López-Rivera J, Leu C, Macnee M, Khoury J, Hoffmann L, Coras R, Kobow K, et al. Journal article, Original article Neuropathology and epilepsy surgery (2022) Hoffmann L, Blümcke I Journal article