Dr. Florian Sure

Lehrstuhl für Physiologie (Vegetative Physiologie)

Automated patch-clamp recordings for detecting activators and inhibitors of the epithelial sodium channel (ENaC) (2025) Sure F, Rapedius M, Diakov A, Bertog M, Obergrussberger A, Fertig N, Korbmacher C, Ilyaskin A Journal article Acute activation of human epithelial sodium channel (ENaC) by serum and glucocorticoid inducible kinase 1 (SGK1) requires prior cleavage of the channel’s γ-subunit at its proximal cleavage site (2025) Diakov A, Sure F, Ilyaskin A, Korbmacher C Journal article Disease-associated missense mutations in the pore loop of polycystin-2 alter its ion channel function in a heterologous expression system (2024) Staudner T, Geiges L, Khamseekaew J, Sure F, Korbmacher C, Ilyaskin A Journal article The small molecule activator S3969 stimulates the epithelial sodium channel by interacting with a specific binding pocket in the channel's β-subunit (2024) Sure F, Einsiedel J, Gmeiner P, Duchstein P, Zahn D, Korbmacher C, Ilyaskin A Journal article Transmembrane Serine Protease 2 and Proteolytic Activation of the Epithelial Sodium Channel in Mouse Kidney (2024) Sure F, Afonso S, Essigke D, Schmidt P, Kalo MZ, Nesterov V, Kißler A, et al. Journal article Transmembrane serine protease 2 (TMPRSS2) proteolytically activates the epithelial sodium channel (ENaC) by cleaving the channel's gamma-subunit (2022) Sure F, Bertog M, Afonso S, Diakov A, Rinke R, Madej MG, Wittmann S, et al. Conference contribution Transmembrane serine protease 2 (TMPRSS2) is involved in proteolytic activation of the epithelial sodium channel (ENaC) in mouse cortical collecting duct (mCCDcl1) cells (2022) Sure F, Afonso S, Bertog M, Rinke R, Wittmann S, Gramberg T, Ilyaskin A, Korbmacher C Conference contribution Transmembrane serine protease 2 (TMPRSS2) proteolytically activates the epithelial sodium channel (ENaC) by cleaving the channel's gamma-subunit (2022) Sure F, Bertog M, Afonso S, Diakov A, Rinke R, Madej MG, Wittmann S, et al. Journal article Proteolytic activation of the epithelial sodium channel (ENaC) by factor VII activating protease (FSAP) and its relevance for sodium retention in nephrotic mice (2021) Artunc F, Bohnert BN, Schneider JC, Staudner T, Sure F, Ilyaskin A, Worn M, et al. Journal article Bile acids inhibit human purinergic receptor P2X4 in a heterologous expression system (2019) Ilyaskin A, Sure F, Nesterov V, Härteis S, Korbmacher C Journal article