Dr. Matthias Schiedel

Lehrstuhl für Pharmazeutische Chemie

Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation (2023) Sinatra L, Vogelmann A, Friedrich F, Tararina MA, Neuwirt E, Colcerasa A, König P, et al. Journal article Fluorescent Ligands Enable Target Engagement Studies for the Intracellular Allosteric Binding Site of the Chemokine Receptor CXCR2 (2023) Huber M, Wurnig S, Toy L, Weiler C, Merten N, Kostenis E, Hansen FK, Schiedel M Journal article Small Molecule Tools to Study Cellular Target Engagement for the Intracellular Allosteric Binding Site of GPCRs (2022) Huber M, Toy L, Schmidt M, Weikert D, Schiedel M Journal article Fluorescent Ligands Targeting the Intracellular Allosteric Binding Site of the Chemokine Receptor CCR2 (2022) Toy L, Huber M, Schmidt M, Weikert D, Schiedel M Journal article Development of a NanoBRET assay to validate inhibitors of Sirt2-mediated lysine deacetylation and defatty-acylation that block prostate cancer cell migration (2022) Vogelmann A, Schiedel M, Woessner N, Merz A, Herp D, Hammelmann S, Colcerasa A, et al. Journal article Comparison of Cellular Target Engagement Methods for the Tubulin Deacetylases Sirt2 and HDAC6: NanoBRET, CETSA, Tubulin Acetylation, and PROTACs (2022) Vogelmann A, Jung M, Hansen FK, Schiedel M Journal article, Review article A Chemical Biology Toolbox Targeting the Intracellular Binding Site of CCR9: Fluorescent Ligands, New Drug Leads and PROTACs (2022) Huber M, Toy L, Schmidt M, Vogt H, Budzinski J, Wiefhoff MFJ, Merten N, et al. Journal article Call for Papers: "epigenetics 2.0" - A Joint Virtual Special Issue on Epigenetics (2021) Bhatia S, Hansen FK, Schiedel M Journal article Validation of the Slow Off-Kinetics of Sirtuin-Rearranging Ligands (SirReals) by Means of Label-Free Electrically Switchable Nanolever Technology (2020) Schiedel M, Daub H, Itzen A, Jung M Journal article HaloTag-Targeted Sirtuin-Rearranging Ligand (SirReal) for the Development of Proteolysis-Targeting Chimeras (PROTACs) against the Lysine Deacetylase Sirtuin 2 (Sirt2) (2020) Schiedel M, Lehotzky A, Szunyogh S, Oláh J, Hammelmann S, Wössner N, Robaa D, et al. Journal article