PD Dr. Stefan Wirtz

Department of Medicine 1 – Gastroenterology, Pneumology and Endocrinology

Integrated multimodel analysis of intestinal inflammation exposes key molecular features of preclinical and clinical IBD (2025) Gonzalez-Acera M, Patankar J, Erkert L, Cineus R, Gamez-Belmonte R, Leupold T, Bubeck M, et al. Journal article Multimodal Profiling of Peripheral Blood Identifies Proliferating Circulating Effector CD4+ T Cells as Predictors for Response to Integrin α4β7-Blocking Therapy in Inflammatory Bowel Disease. (2025) Horn V, Cancino CA, Steinheuer LM, Obermayer B, Fritz K, Nguyen AL, Juhran KS, et al. Journal article Intestinal epithelial Gasdermin C is induced by IL-4R/STAT6 signaling but is dispensable for gut immune homeostasis (2024) Gámez Belmonte MdlR, Wagner Y, Mahapatro M, Wang R, Erkert L, Gonzalez Acera M, Cineus R, et al. Journal article, Original article Spatial Single Cell Profiling Using Imaging Mass Cytometry: Inflammatory Versus Penetrating Crohn's Disease (2024) Lehmann M, Weixler B, Elezkurtaj S, Loddenkemper C, Atreya I, Atreya R, Bacher P, et al. Journal article Distinct Changes in Gut Microbiota of Patients with Kidney Graft Rejection (2024) Visconti V, Wirtz S, Schiffer M, Müller-Deile J Journal article Activation of STAT6 in Intestinal Epithelial Cells Predisposes to Gut Inflammation (2024) Westermann S, Radtke D, Kramer L, Wirtz S, Vöhringer D Journal article Metabolic rewiring controlled by HIF-1α tunes IgA-producing B-cell differentiation and intestinal inflammation (2024) Meng X, Asadi Asadabad S, Cao S, Song R, Lin Z, Safhi M, Qin Y, et al. Journal article Gut Pathobiont–Derived Outer Membrane Vesicles Drive Liver Inflammation and Fibrosis in Primary Sclerosing Cholangitis–Associated Inflammatory Bowel Disease (2024) Dorner H, Stolzer I, Mattner J, Kaminski S, Leistl S, Edrich LM, Schwendner R, et al. Journal article Alzheimer’s disease-related presenilins are key to intestinal epithelial cell function and gut immune homoeostasis (2024) Erkert L, Gamez-Belmonte R, Kabisch M, Schödel L, Patankar J, Gonzalez Acera M, Mahapatro M, et al. Journal article Alpha1-antitrypsin impacts innate host–pathogen interactions with Candida albicans by stimulating fungal filamentation (2024) Jaeger M, Dietschmann A, Austermeier S, Dinçer S, Porschitz P, Vornholz L, Maas RJ, et al. Journal article