Sonderforschungsbereich/Transregio 241/2: Immune-Epithelial Communication in Inflammatory Bowel Diseases (IEC in IBD)

SFB/TR 241/2, TP A02 Mechanisms linking IFNmediated mixed lineage kinase domain-like protein activation with intestinal inflammation SFB/TR 241/2, TP A03 Mucosal immunity as regulator of epithelial cell functions in inflammatory bowel diseases SFB/TR 241/2, TP A06 Molecular mechanisms and therapeutic implications of vascular permeability defects ininflammatory bowel diseases SFB/TR 241/2, TP A07 The Mevalonate pathway as a checkpoint for regulation of prenylation within intestinal epithelial cells in the context of inflammation SFB/TR 241/2, TP A08 Molecular and functional studies on the crosstalk between induced IEL and IECs in intestinal homeostasis and inflammation SFB/TR 241/2, TP B04 Emergency barriers in Inflammatory Bowel Diseases – Neutrophils in the ulcer microenvironment shape epithelial restitution SFB/TR 241/2, TP B05 Impact of epithelial dysfunction on neuroimmune crosstalk in IBD SFB/TR 241/2, TP B08 Direct and indirect crosstalk of epithelial GPR15L with immune cells via the intestinal microbiome in the pathogenesis of IBD SFB/TR 241/2, TP C01 Label-free endoscopic analysis of immune- epithelial communication with advanced optical technologies SFB/TR 241/2, TP C02 Molecular endoscopy to predict response to vedolizumab therapy in ulcerative colitis SFB/TR 241/2, TP C03 Transcranial direct current stimulation for chronic, IBD-associated abdominal pain and the relation of pain perception and the intestinal epithelial barrier SFB/TR 241/2, TP C04 A phase II multi-center clinical trial to study the efficacy and in vivo trafficking of autologous adoptively transferred ex vivo expanded regulatory T cells in patients with ulcerative colitis SFB/TR 241/2, TP Z01 Integrated Research Training Group (iRTG) SFB/TR 241/2, TP Z02 Central Administrative Project SFB/TR 241/2, TP Z03 IBDome Sonderforschungsbereich/Transregio 241/2, Sprecher