Institute of Human Genetics

STAT1 coordinates intestinal epithelial cell death during gastrointestinal infection upstream of Caspase-8 (2021) Stolzer I, Schickedanz L, Chiriac MT, López-Posadas R, Grassl GA, Mattner J, Wirtz S, et al. Journal article Residual homing of alpha 4 beta 7-expressing beta 1(+)PI16(+) regulatory T cells with potent suppressive activity correlates with exposure-efficacy of vedolizumab (2021) Becker E, Dedden M, Gall C, Wiendl M, Ekici AB, Schulz-Kuhnt A, Schweda A, et al. Journal article Generation and characterization of an endogenously tagged SPG11-human iPSC line by CRISPR/Cas9 mediated knock-in (2021) Winner B, Krumm L, Pozner T, Kaindl J, Regensburger M, Günther C, Turan S, et al. Journal article, Original article Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment (2021) Morra A, Escala-Garcia M, Beesley J, Keeman R, Canisius S, Ahearn TU, Andrulis IL, et al. Journal article β2-microglobulin triggers NLRP3 inflammasome activation in tumor-associated macrophages to promote multiple myeloma progression (2021) Hofbauer D, Mougiakakos D, Broggini L, Zaiss M, Büttner-Herold M, Bach C, Spriewald B, et al. Journal article The gut-brain axis in inflammatory bowel disease—current and future perspectives (2021) Günther C, Rothhammer V, Karow M, Neurath M, Winner B Journal article, Review article Pleiotropy-guided transcriptome imputation from normal and tumor tissues identifies candidate susceptibility genes for breast and ovarian cancer (2021) Kar SP, Considine DP, Tyrer JP, Plummer JT, Chen S, Dezem FS, Barbeira AN, et al. Journal article Axon-Specific Mitochondrial Pathology in SPG11 Alpha Motor Neurons (2021) Güner F, Pozner T, Krach F, Prots I, Loskarn S, Schlötzer-Schrehardt U, Winkler J, et al. Journal article scRNA sequencing uncovers a TCF4-dependent transcription factor network regulating commissure development in mouse (2021) Wittmann MT, Katada S, Sock E, Kirchner P, Ekici AB, Wegner M, Nakashima K, et al. Journal article, Original article Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element (2021) Baxter JS, Johnson N, Tomczyk K, Gillespie A, Maguire S, Brough R, Fachal L, et al. Journal article