Professur für Genetik

Human CD22 cannot fully substitute murine CD22 functions in vivo, as shown in a new knockin mouse model (2012) Wöhner M, Born S, Nitschke L Journal article Targeting of CD22-positive B-cell lymphoma cells by synthetic divalent sialic acid analogues (2012) Schweizer A, Wöhner M, Prescher H, Brossmer R, Nitschke L Journal article Regulation of B cell functions by the sialic acid-bincing receptors Siglec-G and CD22 (2012) Jellusova J, Nitschke L Journal article, Review article A hypomorphic IgH-chain allele affects development of B-cell subsets and favours receptor editing (2011) Brenner S, Drewel D, Steinbart T, Weisel F, Härtel E, Pötzsch S, Welzel H, et al. Journal article Grb2 regulates B-cell maturation, B-cell memory responses and inhibits B-cell Ca2+ signalling (2011) Ackermann J, Radtke D, Maurberger A, Winkler T, Nitschke L Journal article NFATc1 affects mouse splenic B cell function by controlling the calcineurin-NFAT signaling network (2011) Bhattacharyya S, Deb J, Patra AK, Duong Anh Thuy Pham , Chen W, Vaeth M, Berberich-Siebelt F, et al. Journal article Siglec-G Regulates B1 Cell Survival and Selection (2010) Jellusova J, Dueber S, Gueckel E, Binder CJ, Weiss S, Voll R, Nitschke L Journal article CD22 x Siglec-G Double-Deficient Mice Have Massively Increased B1 Cell Numbers and Develop Systemic Autoimmunity (2010) Jellusova J, Wellmann U, Amann KU, Winkler T, Nitschke L Journal article Swiprosin-1/EFhd2 Controls B Cell Receptor Signaling through the Assembly of the B Cell Receptor, Syk, and Phospholipase C gamma 2 in Membrane Rafts (2010) Kroczek C, Lang C, Brachs S, Grohmann M, Duetting S, Schweizer A, Nitschke L, et al. Journal article CD22 and Siglec-G: B-cell inhibitory receptors with distinct functions (2009) Nitschke L Journal article, Review article