Professur für CAR-T-Zell-Therapie

Energy metabolism is co-determined by genetic variants in chronic lymphocytic leukemia and influences drug sensitivity (2019) Lu J, Böttcher M, Walther T, Mougiakakos D, Zenz T, Huber W Journal article Inflammation-induced glycolytic switch controls suppressivity of mesenchymal stem cells via STAT1 glycosylation (2019) Jitschin R, Böttcher M, Saul D, Lukassen S, Bruns H, Loschinski R, Ekici AB, et al. Journal article A novel immunoregulatory function of beta-2-microglobulin as a promoter of myeloid derived suppressor cell induction (2019) Bruns H, Jitschin S, Gamali S, Saul D, Böttcher M, Mackensen A, Jitschin R, Mougiakakos D Journal article Prolyl Hydroxylase 3 (Phd3) Is a Therapeutic Target in Isocitrate Dehydrogenase 1 (IDH1) Mutated Acute Myeloid Leukemia (2018) Chaturvedi A, Cruz MMA, Goparaju R, Gabdoulline R, Schottmann R, Goerlich K, Kloos A, et al. Conference contribution Role of N6-Methyladenosine (m6A) RNA Modification in Multiple Myeloma (2018) Bach C, Leffler M, Flamann C, Kronke J, Mougiakakos D, Mackensen A, Bruns H Conference contribution Stroma Cells Promote a S100A8/A9(high)-Subset of AML Blasts with Distinct Metabolic Features in a Jak/STAT3-Dependent Manner (2018) Böttcher M, Panagiotidis K, Mackensen A, Mougiakakos D Conference contribution Regulation of Energy Metabolism during Early B Lymphocyte Development (2018) Urbanczyk S, Stein M, Schuh W, Jäck HM, Mougiakakos D, Mielenz D Journal article Phenotypic and functional alterations of myeloid-derived suppressor cells during the disease course of multiple sclerosis (2018) Iacobaeus E, Douagi I, Jitschin R, Marcusson-Stahl M, Andren AT, Gavin C, Lefsihane K, et al. Journal article CD33/CD3-bispecific T-cell engaging (BiTE®) antibody construct targets monocytic AML myeloid-derived suppressor cells (2018) Jitschin R, Saul D, Braun M, Tohumeken S, Kischel R, Lutteropp M, Dos Santos C, et al. Journal article D-2-hydroxyglutarate interferes with HIF-1α stability skewing T-cell metabolism towards oxidative phosphorylation and impairing Th17 polarization (2018) Böttcher M, Renner K, Berger R, Mentz K, Thomas S, Cardenas-Conejo ZE, Dettmer K, et al. Journal article