Structural characterization of the phospholipid stabilizer layer at the solid-liquid interface of dispersed triglyceride nanocrystals with small-angle x-ray and neutron scattering

Schmiele M, Schindler T, Unruh T, Busch S, Morhenn H, Westermann M, Steiniger F, Radulescu A, Lindner P, Schweins R, Boesecke P (2013)

Publication Status: Published

Publication Type: Journal article, Original article

Publication year: 2013

Journal

Physical Review E American Physical Society

Book Volume: 87

Article Number: 062316

Journal Issue: 6

DOI: 10.1103/PhysRevE.87.062316

Abstract

Dispersions of crystalline nanoparticles with at least one sufficiently large unit cell dimension can give rise to Bragg reflections in the small-angle scattering range. If the nanocrystals possess only a small number of unit cells along these particular crystallographic directions, the corresponding Bragg reflections will be broadened. In a previous study of phospholipid stabilized dispersions of β-tripalmitin platelets, the x-ray powder pattern simulation analysis (XPPSA) was developed. The XPPSA method facilitates the interpretation of the rather complicated small-angle x-ray scattering (SAXS) curves of such dispersions of nanocrystals. The XPPSA method yields the distribution function of the platelet thicknesses and facilitates a structural characterization of the phospholipid stabilizer layer at the solid-liquid interface between the nanocrystals and the dispersion medium from the shape of the broadened 001 Bragg reflection. In this contribution an improved and extended version of the XPPSA method is presented. The SAXS and small-angle neutron scattering patterns of dilute phospholipid stabilized tripalmitin dispersions can be reproduced on the basis of a consistent simulation model for the particles and their phospholipid stabilizer layer on an absolute scale. The results indicate a surprisingly flat arrangement of the phospholipid molecules in the stabilizer layer with a total thickness of only 12 Å. The stabilizer layer can be modeled by an inner shell for the fatty acid chains and an outer shell including the head groups and additional water. The experiments support a dense packing of the phospholipid molecules on the nanocrystal surfaces rather than isolated phospholipid domains. © 2013 American Physical Society.

Authors with CRIS profile

Martin Schmiele Professur für Nanomaterialcharakterisierung (Streumethoden) Torben Schindler Professur für Nanomaterialcharakterisierung (Streumethoden) Tobias Unruh Professur für Nanomaterialcharakterisierung (Streumethoden)

Additional Organisation(s)

Exzellenz-Cluster Engineering of Advanced Materials

Involved external institutions

Technische Universität München (TUM) DE Germany (DE) Universitätsklinikum Jena DE Germany (DE) Forschungszentrum Jülich / Research Centre Jülich (FZJ) DE Germany (DE) Institute Laue-Langevin (ILL) FR France (FR) European Synchrotron Radiation Facility (ESRF) FR France (FR)

How to cite

APA:

Schmiele, M., Schindler, T., Unruh, T., Busch, S., Morhenn, H., Westermann, M.,... Boesecke, P. (2013). Structural characterization of the phospholipid stabilizer layer at the solid-liquid interface of dispersed triglyceride nanocrystals with small-angle x-ray and neutron scattering. Physical Review E, 87(6). https://dx.doi.org/10.1103/PhysRevE.87.062316

MLA:

Schmiele, Martin, et al. "Structural characterization of the phospholipid stabilizer layer at the solid-liquid interface of dispersed triglyceride nanocrystals with small-angle x-ray and neutron scattering." Physical Review E 87.6 (2013).

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