Regulatory and Cellular Functions of Plant RhoGAPs and RhoGDIs

Kost B (2010)


Publication Type: Book chapter / Article in edited volumes

Publication year: 2010

Publisher: Springer-Verlag Berlin Heidelberg

Edited Volumes: Integrated G Proteins Signaling in Plants

Series: Signaling and Communication in Plants

Pages Range: 27-48

ISBN: 978-3-642-03523-4

DOI: 10.1007/978-3-642-03524-1_2

Abstract

Rho GTPases play central roles in the regulation of essential cellular
processes, such as directional expansion, motility, and division. RhoGEFs (Guanine
Nucleotide Exchange Factors) have key functions in the stimulus-induced spatiotemporal
control of Rho GTPase activity. RhoGAPs (GTPase activating proteins)
and RhoGDIs (Guanine nucleotide dissociation inhibitors) have long been seen as
less important regulators of Rho GTPase activity, with functions largely restricted
to the constitutive attenuation of Rho signaling. Extended families of diverse
RhoGAPs, as well as small families of structurally similar RhoGDIs, have been
identified in yeast, animals, and plants. Recent research has established that members
of these protein families play much more important and complex roles than
previously anticipated in the regulation of Rho GTPase activity and cellular processes.
Non-plant RhoGAPs and RhoGDIs were shown to be tightly regulated by
upstream signaling, and the same is likely to be true for their plant homologs as
well. The recent functional characterization of plant RhoGAPs and RhoGDIs has
allowed exciting and universally important insights into the molecular mechanisms
underlying the control of Rho GTPase activity by these proteins.

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How to cite

APA:

Kost, B. (2010). Regulatory and Cellular Functions of Plant RhoGAPs and RhoGDIs. In Yalovsky, Shaul, Baluška, František, Jones, Alan (Eds.) (Eds.), Integrated G Proteins Signaling in Plants. (pp. 27-48). Springer-Verlag Berlin Heidelberg.

MLA:

Kost, Benedikt. "Regulatory and Cellular Functions of Plant RhoGAPs and RhoGDIs." Integrated G Proteins Signaling in Plants. Ed. Yalovsky, Shaul, Baluška, František, Jones, Alan (Eds.), Springer-Verlag Berlin Heidelberg, 2010. 27-48.

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