Split-spectrum amplitude-decorrelation angiography with optical coherence tomography

Jia Y, Tan O, Tokayer J, Potsaid B, Wang Y, Liu JJ, Kraus M, Subhash H, Fujimoto JG, Hornegger J, Huang D (2012)

Publication Type: Journal article, Original article

Publication year: 2012

Journal

Optics Express Optical Society of America

Original Authors: Jia Y., Tan O., Tokayer J., Potsaid B., Wang Y., Liu J., Kraus M., Subhash H., Fujimoto J., Hornegger J., Huang D.

Publisher: Optical Society of America

Book Volume: 20

Pages Range: 4710-4725

Journal Issue: 4

DOI: 10.1364/OE.20.004710

Abstract

Amplitude decorrelation measurement is sensitive to transverse flow and immune to phase noise in comparison to Doppler and other phase-based approaches. However, the high axial resolution of OCT makes it very sensitive to the pulsatile bulk motion noise in the axial direction. To overcome this limitation, we developed split-spectrum amplitude-decorrelation angiography (SSADA) to improve the signal-to-noise ratio (SNR) of flow detection. The full OCT spectrum was split into several narrower bands. Inter-B-scan decorrelation was computed using the spectral bands separately and then averaged. The SSADA algorithm was tested on in vivo images of the human macula and optic nerve head. It significantly improved both SNR for flow detection and connectivity of microvascular network when compared to other amplitude-decorrelation algorithms. © 2012 Optical Society of America.

Authors with CRIS profile

Martin Kraus Lehrstuhl für Informatik 14 (Bild- und Sprachverarbeitung) Joachim Hornegger Lehrstuhl für Informatik 14 (Bild- und Sprachverarbeitung)

Involved external institutions

Oregon Health and Science University (OSHU) US United States (USA) (US) University of Southern California (USC) US United States (USA) (US) Massachusetts Institute of Technology (MIT) US United States (USA) (US)

How to cite

APA:

Jia, Y., Tan, O., Tokayer, J., Potsaid, B., Wang, Y., Liu, J.J.,... Huang, D. (2012). Split-spectrum amplitude-decorrelation angiography with optical coherence tomography. Optics Express, 20(4), 4710-4725. https://dx.doi.org/10.1364/OE.20.004710

MLA:

Jia, Yali, et al. "Split-spectrum amplitude-decorrelation angiography with optical coherence tomography." Optics Express 20.4 (2012): 4710-4725.

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