Riexinger A, Laun FB, Bickelhaupt S, Seuß H, Uder M, Hensel B, Saake M (2020)
Publication Type: Journal article
Publication year: 2020
Book Volume: 15
Article Number: e0239743
Journal Issue: 10 October
DOI: 10.1371/journal.pone.0239743
Purpose The purpose of this study was to investigate whether the cardiac motion artifact that regularly appears in diffusion-weighted imaging of the left liver lobe might be reduced by acquiring images in inspiration, when the coupling between heart and liver might be minimal. Materials and methods 43 patients with known or suspected focal liver lesions were examined at 1.5 T with breath hold acquisition, once in inspiration and once in expiration. Data were acquired with a diffusion-weighted echo planar imaging sequence and two b-values (b50 = 50 s/mm2 and b800 = 800 s/mm2). The severity of the cardiac motion artifact in the left liver lobe was rated by two experienced radiologists for both b-values with a 5 point Likert scale. Additionally, the normalized signal S(b800)/S(b50) in the left liver lobe was computed. The Wilcoxon signed-rank test was used comparing the scores of the two readers obtained in inspiration and expiration, and to compare the normalized signal in inspiration and expiration. Results The normalized signal in inspiration was slightly higher than in expiration (0.349±0.077 vs 0.336±0.058), which would indicate a slight reduction of the cardiac motion artifact, but this difference was not significant (p = 0.24). In the qualitative evaluation, the readers did not observe a significant difference for b50 (reader 1: p = 0.61; reader 2: p = 0.18). For b800, reader 1 observed a significant difference of small effect size favouring expiration (p = 0.03 with a difference of mean Likert scores of 0.27), while reader 2 observed no significant difference (p = 0.62). Conclusion Acquiring the data in inspiration does not lead to a markedly reduced cardiac motion artifact in diffusion-weighted imaging of the left liver lobe and is in this regard not to be preferred over acquiring the data in expiration.
APA:
Riexinger, A., Laun, F.B., Bickelhaupt, S., Seuß, H., Uder, M., Hensel, B., & Saake, M. (2020). On the dependence of the cardiac motion artifact on the breathing cycle in liver diffusion-weighted imaging. PLoS ONE, 15(10 October). https://doi.org/10.1371/journal.pone.0239743
MLA:
Riexinger, Andreas, et al. "On the dependence of the cardiac motion artifact on the breathing cycle in liver diffusion-weighted imaging." PLoS ONE 15.10 October (2020).
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