A mixed waveform protocol for reduction of the cardiac motion artifact in black-blood diffusion-weighted imaging of the liver
Rauh SS, Riexinger A, Ohlmeyer S, Hammon M, Saake M, Stemmer A, Uder M, Hensel B, Laun FB (2020)
Publication Type: Journal article
Publication year: 2020
Journal
Book Volume: 67
Pages Range: 59-68
DOI: 10.1016/j.mri.2019.12.011
Abstract
Objective: Diffusion-weighted imaging (DWI) in the liver suffers from signal loss due to the cardiac motion artifact, especially in the left liver lobe. The purpose of this work was to improve the image quality of liver DWI in terms of cardiac motion artifact reduction and achievement of black-blood images in low b-value images. Material and methods: Ten healthy volunteers (age 20–31 years) underwent MRI examinations at 1.5 T with a prototype DWI sequence provided by the vendor. Two diffusion encodings (i.e. waveforms), monopolar and flow-compensated, and the b-values 0, 20, 50, 100, 150, 600 and 800 s/mm2 were used. Two Likert scales describing the severity of the pulsation artifact and the quality of the black-blood state were defined and evaluated by two experienced radiologists. Regions of interest (ROIs) were manually drawn in the right and left liver lobe in each slice and combined to a volume of interest (VOI). The mean and coefficient of variation were calculated for each normalized VOI-averaged signal to assess the severity of the cardiac motion artifact. The ADC was calculated using two b-values once for the monopolar data and once with mixed data, using the monopolar data for the small and the flow-compensated data for the high b-value. A Wilcoxon rank sum test was used to compare the Likert scores obtained for monopolar and flow-compensated data. Results: At b-values from 20 to 150 s/mm2, unlike the flow-compensated diffusion encoding, the monopolar encoding yielded black blood in all images with a negligible signal loss due to the cardiac motion artifact. At the b-values 600 and 800 s/mm2, the flow-compensated encoding resulted in a significantly reduced cardiac motion artifact, especially in the left liver lobe, and in a black-blood state. The ADC calculated with monopolar data was significantly higher in the left than in the right liver lobe. Conclusion: It is recommendable to use the following mixed waveform protocol: Monopolar diffusion encodings at small b-values and flow-compensated diffusion encodings at high b-values.
Authors with CRIS profile
Andreas Riexinger
Institute of Radiology
Sabine Ohlmeyer
Institute of Radiology
Matthias Hammon
Institute of Radiology
Marc Saake
Medizinische Fakultät
Michael Uder
Lehrstuhl für Diagnostische Radiologie
Bernhard Hensel
Max Schaldach-Stiftungsprofessur für Biomedizinische Technik
Frederik Bernd Laun
Professur für quantitative MR-Bildgebung (Heisenberg-Professur)
Involved external institutions
Netherlands (NL)How to cite
APA:
Rauh, S.S., Riexinger, A., Ohlmeyer, S., Hammon, M., Saake, M., Stemmer, A.,... Laun, F.B. (2020). A mixed waveform protocol for reduction of the cardiac motion artifact in black-blood diffusion-weighted imaging of the liver. Magnetic Resonance Imaging, 67, 59-68. https://doi.org/10.1016/j.mri.2019.12.011
MLA:
Rauh, Susanne S., et al. "A mixed waveform protocol for reduction of the cardiac motion artifact in black-blood diffusion-weighted imaging of the liver." Magnetic Resonance Imaging 67 (2020): 59-68.
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