Spectral-domain optical coherence tomography findings of the macula in 500 consecutive patients with uveitis

Grajewski RS, Boelke AC, Adler W, Meyer S, Caramoy A, Kirchhof B, Cursiefen C, Heindl LM (2016)


Publication Type: Journal article

Publication year: 2016

Journal

Book Volume: 30

Pages Range: 1415-1423

Journal Issue: 11

DOI: 10.1038/eye.2016.133

Abstract

PurposeTo analyze the macular structure in a large series of consecutive patients with different types of uveitis using spectral-domain optical coherence tomography (SD-OCT).Patients and methodsFive hundred eyes of 500 consecutive patients with anterior, intermediate, posterior, and panuveitis underwent standardized macular examination using SD-OCT. Central retinal thickness (CRT), macular volume (MV), and presence of cystoid macular edema (CME), diffuse macular edema (DME), serous retinal detachment (SRD), epiretinal membrane with (ERM+) and without (ERM-) retinal surface wrinkling were determined.ResultsThe anatomic location of inflammation affected significantly CRT and MV (P<0.001, respectively), with the highest values in intermediate and panuveitis. CME was seen in 25% of all uveitic eyes, DME in 11%, SRD in 8%, ERM+ in 18%, and ERM- in 13%. CME was most frequent in intermediate (40%) and panuveitis (36%); DME was most frequent in panuveitis (18%) and posterior uveitis (17%); SRD was most frequent in panuveitis (15%) and posterior uveitis (10%); ERM+ was most frequent in panuveitis (45%) and intermediate uveitis (30%); and ERM- was most frequent in intermediate (14%) and posterior uveitis (15%).ConclusionSD-OCT of the macula is recommended for all uveitis patients. CRT, MV, and the incidence of CME were highest in intermediate and panuveitis.

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APA:

Grajewski, R.S., Boelke, A.C., Adler, W., Meyer, S., Caramoy, A., Kirchhof, B.,... Heindl, L.M. (2016). Spectral-domain optical coherence tomography findings of the macula in 500 consecutive patients with uveitis. Eye, 30(11), 1415-1423. https://dx.doi.org/10.1038/eye.2016.133

MLA:

Grajewski, R. S., et al. "Spectral-domain optical coherence tomography findings of the macula in 500 consecutive patients with uveitis." Eye 30.11 (2016): 1415-1423.

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