Sahu S, Quesne MG, Davies CG, Dürr M, Ivanovic-Burmazovic I, Siegler MA, Jameson GN, de Visser SP, Goldberg DP (2014)
Publication Status: Published
Publication Type: Journal article, Original article
Publication year: 2014
Publisher: American Chemical Society
Book Volume: 136
Pages Range: 13542-13545
Journal Issue: 39
DOI: 10.1021/ja507346t
The synthesis of a pentadentate ligand with strategically designed fluorinated arene groups in the second coordination sphere of a nonheme iron center is reported. The oxidatively resistant fluorine substituents allow for the trapping and characterization of an Fe(O) complex at ?20 °C. Upon warming of the Fe(O) complex an unprecedented arene C-F hydroxylation reaction occurs. Computational studies support the finding that substrate orientation is a critical factor in the observed reactivity. This work not only gives rare direct evidence for the participation of an Fe(O) species in arene hydroxylation but also provides the first example of a high-valent iron-oxo complex that mediates aromatic C-F hydroxylation.
APA:
Sahu, S., Quesne, M.G., Davies, C.G., Dürr, M., Ivanovic-Burmazovic, I., Siegler, M.A.,... Goldberg, D.P. (2014). Direct observation of a nonheme iron(IV)-oxo complex that mediates aromatic c-f hydroxylation. Journal of the American Chemical Society, 136(39), 13542-13545. https://dx.doi.org/10.1021/ja507346t
MLA:
Sahu, Sumit, et al. "Direct observation of a nonheme iron(IV)-oxo complex that mediates aromatic c-f hydroxylation." Journal of the American Chemical Society 136.39 (2014): 13542-13545.
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