The effect of coating type on mechanical properties and controlled drug release of PCL/zein coated 45S5 bioactive glass scaffolds for bone tissue engineering

Fereshteh Z, Nooeaid P, Fathi M, Bagri A, Boccaccini AR (2015)

Publication Status: Published

Publication Type: Journal article, Original article

Publication year: 2015

Journal

Materials Science and Engineering C Elsevier

Publisher: Elsevier

Book Volume: 54

Pages Range: 50-60

DOI: 10.1016/j.msec.2015.05.011

Abstract

A highly investigated branch of tissue engineering involves the implantation of a highly porous biomaterial scaffold populated with appropriate cells to provide a three-dimensional (3D) environment in which new tissue can grow. As a drawback, the mechanical properties of foam-like BG-based scaffolds are in general poor in terms of strength and toughness for bone tissue engineering applications. Polymer coatings have been proposed to toughen brittle scaffolds, which can be achieved by the formation of a surface coating and by impregnation of microcracks and surface pores with a suitable polymer. The Fourier transform infrared (FTIR) spectra of different scaffolds were recorded on a Nicolet 6700 FTIR spectrometer in transmittance mode in the mid infrared region. Amounts of the released drugs at specified time periods were plotted as percentage of drug released versus time. The drug release evaluation was performed using 5 samples for each time up to 14 days and obtained results were expressed as the mean values and standard deviations.

Authors with CRIS profile

Patcharakamon Nooeaid Lehrstuhl für Werkstoffwissenschaften (Biomaterialien) Aldo Boccaccini Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)

Involved external institutions

Isfahan University of Technology (IUT) / دانشگاه صنعتی اصفهان IR Iran, Islamic Republic of (IR) Massachusetts Institute of Technology (MIT) US United States (USA) (US)

How to cite

APA:

Fereshteh, Z., Nooeaid, P., Fathi, M., Bagri, A., & Boccaccini, A.R. (2015). The effect of coating type on mechanical properties and controlled drug release of PCL/zein coated 45S5 bioactive glass scaffolds for bone tissue engineering. Materials Science and Engineering C, 54, 50-60. https://dx.doi.org/10.1016/j.msec.2015.05.011

MLA:

Fereshteh, Zeinab, et al. "The effect of coating type on mechanical properties and controlled drug release of PCL/zein coated 45S5 bioactive glass scaffolds for bone tissue engineering." Materials Science and Engineering C 54 (2015): 50-60.

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