Article in Edited Volumes
(Original article)


Vito – a generic agent for multi-physics model personalization: Application to heart modeling


Publication Details
Author(s): Neumann D, Mansi T, Itu L, Georgescu B, Kayvanpour E, Sedaghat-Hamedani F, Haas J, Katus H, Meder B, Steidl S, Hornegger J, Comaniciu D
Editor(s): Navab N., Hornegger J., Wells W. M., and Frangi A. F.
Title edited volumes: Medical Image Computing and Computer-Assisted Intervention – MICCAI 2015, 18th International Conference, Munich, Germany, October 5–9, 2015, Proceedings, Part II
Publisher: Springer Verlag
Publishing place: Cham, Heidelberg, New York, Dordrecht, London
Publication year: 2015
Title of series: Lecture Notes in Computer Science
Volume: 9350
Pages range: 442-449
ISBN: 9783319245706
Event: 18th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2015

Abstract

Precise estimation of computational physiological model parameters from patient data is one of the main hurdles towards their clinical applicability. Designing robust estimation algorithms is often a tedious and model-specific process. We propose to use, for the first time to our knowledge, artificial intelligence (AI) concepts to learn how to personalize a computational model, inspired by how an expert manually personalizes. We reformulate the parameter estimation problem in terms of Markov decision process and reinforcement learning. In an off-line phase, the artificial agent, called Vito, automatically learns a representative state-action-state model through data-driven exploration of the computational model under consideration. In other words, Vito learns how the model behaves under change of parameters and how to personalize it. Vito then controls the on-line personalization by exploiting its automatically derived action policy. Because the algorithm is model-independent, personalizing a completely new model would require only adjusting some simple parameters of the agent and defining the observations to match, without the full knowledge of the model itself. Vito was evaluated on two challenging problems: the inverse problem of cardiac electrophysiology and the personalization of a lumped-parameter whole-body circulation model. Obtained results suggested that Vito could achieve equivalent goodness of fit than standard methods, while being more robust (up to 25% higher success rates) and with faster (up to three times) convergence rate. Our AI approach could thus make model personalization algorithms generalizable and self-adaptable to any patient, like a human operator.



How to cite
APA: Neumann, D., Mansi, T., Itu, L., Georgescu, B., Kayvanpour, E., Sedaghat-Hamedani, F.,... Comaniciu, D. (2015). Vito – a generic agent for multi-physics model personalization: Application to heart modeling. In Navab N., Hornegger J., Wells W. M., and Frangi A. F. (Eds.), Medical Image Computing and Computer-Assisted Intervention – MICCAI 2015, 18th International Conference, Munich, Germany, October 5–9, 2015, Proceedings, Part II (pp. 442-449). Cham, Heidelberg, New York, Dordrecht, London: Springer Verlag.

MLA: Neumann, Dominik, et al. "Vito – a generic agent for multi-physics model personalization: Application to heart modeling." Medical Image Computing and Computer-Assisted Intervention – MICCAI 2015, 18th International Conference, Munich, Germany, October 5–9, 2015, Proceedings, Part II Ed. Navab N., Hornegger J., Wells W. M., and Frangi A. F., Cham, Heidelberg, New York, Dordrecht, London: Springer Verlag, 2015. 442-449.

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