Journal article


Experimental and theoretical approaches to the protonation of thiourea: A convenient nucleophile in coordination chemistry revisited


Publication Details
Author(s): Schiessl W, Summa N, Weber C, Gubo S, Dücker-Benfer C, Puchta R, van Eikema Hommes N, van Eldik R
Publisher: Wiley-VCH Verlag
Publication year: 2005
Volume: 631
Journal issue: 13-14
Pages range: 2812-2819
ISSN: 0044-2313

Abstract

The protonation of thiourea was reinvestigated in aqueous and non-aqueous media using potentiometric, UV-vis, NMR, MS spectroscopy, as well as DFT calculations. In aqueous medium, no evidence for protonation could be found in the pH range 0 to 7, in agreement with typical pK(a) values (acid dissociation constants of protonated thiourea) quoted in the literature of around - 1.2. Most of the protonation constants quoted in the literature are incorrect and apparently refer to pK, values. Protonation of thiourea occurs at a much higher pK, value in methanol and in water-dioxane mixtures, which must be related to the stabilization of the protonated species in such media.



How to cite
APA: Schiessl, W., Summa, N., Weber, C., Gubo, S., Dücker-Benfer, C., Puchta, R.,... van Eldik, R. (2005). Experimental and theoretical approaches to the protonation of thiourea: A convenient nucleophile in coordination chemistry revisited. Zeitschrift für Anorganische und Allgemeine Chemie, 631(13-14), 2812-2819. https://dx.doi.org/10.1002/zaac.200500157

MLA: Schiessl, Wolfgang, et al. "Experimental and theoretical approaches to the protonation of thiourea: A convenient nucleophile in coordination chemistry revisited." Zeitschrift für Anorganische und Allgemeine Chemie 631.13-14 (2005): 2812-2819.

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