Journal article

Depth-encoded all-fiber swept source polarization sensitive OCT

Publication Details
Author(s): Wang Z, Lee HC, Ahsen OO, Lee B, Choi W, Potsaid B, Liu J, Jayaraman V, Cable A, Kraus M, Liang K, Hornegger J, Fujimoto JG
Publisher: Optical Society of America
Publication year: 2014
Volume: 5
Pages range: 2931-2949
ISSN: 2156-7085


Polarization sensitive optical coherence tomography (PS-OCT) is a functional extension of conventional OCT and can assess depth-resolved tissue birefringence in addition to intensity. Most existing PS-OCT systems are relatively complex and their clinical translation remains difficult. We present a simple and robust all-fiber PS-OCT system based on swept source technology and polarization depth-encoding. Polarization multiplexing was achieved using a polarization maintaining fiber. Polarization sensitive signals were detected using fiber based polarization beam splitters and polarization controllers were used to remove the polarization ambiguity. A simplified post-processing algorithm was proposed for speckle noise reduction relaxing the demand for phase stability. We demonstrated systems design for both ophthalmic and catheter-based PS-OCT. For ophthalmic imaging, we used an optical clock frequency doubling method to extend the imaging range of a commercially available short cavity light source to improve polarization depth-encoding. For catheter based imaging, we demonstrated 200 kHz PS-OCT imaging using a MEMS-tunable vertical cavity surface emitting laser (VCSEL) and a high speed micromotor imaging catheter. The system was demonstrated in human retina, finger and lip imaging, as well as ex vivo swine esophagus and cardiovascular imaging. The all-fiber PS-OCT is easier to implement and maintain compared to previous PS-OCT systems and can be more easily translated to clinical applications due to its robust design. (C) 2014 Optical Society of America

How to cite
APA: Wang, Z., Lee, H.-C., Ahsen, O.O., Lee, B., Choi, W., Potsaid, B.,... Fujimoto, J.G. (2014). Depth-encoded all-fiber swept source polarization sensitive OCT. Biomedical Optics Express, 5, 2931-2949.

MLA: Wang, Zhao, et al. "Depth-encoded all-fiber swept source polarization sensitive OCT." Biomedical Optics Express 5 (2014): 2931-2949.

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