DRACO: differentiable reconstruction for arbitrary CBCT orbits

Ye C, Schneider LS, Sun Y, Thies M, Mei S, Maier A (2025)


Publication Language: English

Publication Type: Journal article

Publication year: 2025

Journal

Book Volume: 70

Article Number: 075005

Journal Issue: 7

DOI: 10.1088/1361-6560/adbb50

Abstract

Objective. This study introduces a novel method for reconstructing cone beam computed tomography (CBCT) images for arbitrary orbits, addressing the computational and memory challenges associated with traditional iterative reconstruction algorithms. Approach. The proposed method employs a differentiable shift-variant filtered backprojection neural network, optimized for arbitrary trajectories. By integrating known operators into the learning model, the approach minimizes the number of trainable parameters while enhancing model interpretability. This framework adapts seamlessly to specific orbit geometries, including non-continuous trajectories such as circular-plus-arc or sinusoidal paths, enabling faster and more accurate CBCT reconstructions. Main results. Experimental validation demonstrates that the method significantly accelerates reconstruction, reducing computation time by over 97% compared to conventional iterative algorithms. It achieves superior or comparable image quality with reduced noise, as evidenced by a 38.6% reduction in mean squared error, a 7.7% increase in peak signal-to-noise ratio, and a 5.0% improvement in the structural similarity index measure. The flexibility and robustness of the approach are confirmed through its ability to handle data from diverse scan geometries. Significance. This method represents a significant advancement in interventional medical imaging, particularly for robotic C-arm CT systems, enabling real-time, high-quality CBCT reconstructions for customized orbits. It offers a transformative solution for clinical applications requiring computational efficiency and precision in imaging.

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How to cite

APA:

Ye, C., Schneider, L.-S., Sun, Y., Thies, M., Mei, S., & Maier, A. (2025). DRACO: differentiable reconstruction for arbitrary CBCT orbits. Physics in Medicine and Biology, 70(7). https://doi.org/10.1088/1361-6560/adbb50

MLA:

Ye, Chengze, et al. "DRACO: differentiable reconstruction for arbitrary CBCT orbits." Physics in Medicine and Biology 70.7 (2025).

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