THz Metamaterial Biodetection Platform for Label-Free, Sensitive and Selective DNA-, Protein- or Supermolecular-Based Biomarker Analysis

Richter M, Loth Y, Rachinger N, Wigger AK, Boßerhoff AK, Bolívar PH (2024)

Publication Type: Conference contribution

Publication year: 2024

Publisher: SPIE

Book Volume: 12994

Conference Proceedings Title: Proceedings of SPIE - The International Society for Optical Engineering

Event location: Strasbourg, FRA

ISBN: 9781510673069

DOI: 10.1117/12.3016084

Abstract

This work is dedicated to present a versatile, metamaterial-based sensing platform for biomarker detection in the THz frequency regime. The sensor can be classified as frequency selective surface and exhibits a characteristic dual resonance feature in the transmission frequency response which has been proven to perform well in biosensing applications. The platform is able to selectively detect proteins such as transcription factor EGR2 (early growth response protein 2) from a complex sample matrix with more than 7 · 103 other protein species, to sensitively detect reverse-transcribed MIA (melanoma inhibitory activity) DNA from a complex sample matrix and to respond to extracellular vesicular structures as well.

Authors with CRIS profile

Nicole Rachinger Lehrstuhl für Biochemie und Molekulare Medizin Anja Katrin Boßerhoff Lehrstuhl für Biochemie und Molekulare Medizin

Involved external institutions

Universität Siegen DE Germany (DE)

How to cite

APA:

Richter, M., Loth, Y., Rachinger, N., Wigger, A.K., Boßerhoff, A.K., & Bolívar, P.H. (2024). THz Metamaterial Biodetection Platform for Label-Free, Sensitive and Selective DNA-, Protein- or Supermolecular-Based Biomarker Analysis. In Mona Jarrahi, Sascha Preu, Dmitry Turchinovich (Eds.), Proceedings of SPIE - The International Society for Optical Engineering. Strasbourg, FRA: SPIE.

MLA:

Richter, Merle, et al. "THz Metamaterial Biodetection Platform for Label-Free, Sensitive and Selective DNA-, Protein- or Supermolecular-Based Biomarker Analysis." Proceedings of the Terahertz Photonics III 2024, Strasbourg, FRA Ed. Mona Jarrahi, Sascha Preu, Dmitry Turchinovich, SPIE, 2024.

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