Exploring Epipolar Consistency Conditions for Rigid Motion Compensation in In-vivo X-ray Microscopy

Thies M, Wagner F, Gu M, Mei S, Huang Y, Pechmann S, Aust O, Weidner D, Neag G, Uderhardt S, Schett G, Christiansen S, Maier A (2024)

Publication Type: Conference contribution

Publication year: 2024

Journal

Publisher: Springer Science and Business Media Deutschland GmbH

Pages Range: 211-216

Conference Proceedings Title: Informatik aktuell

Event location: Erlangen, DEU

ISBN: 9783658440367

URI: https://arxiv.org/abs/2303.00449

DOI: 10.1007/978-3-658-44037-4_60

Abstract

Intravital X-ray microscopy (XRM) in preclinical mouse models is of vital importance for the identification of microscopic structural pathological changes in the bone which are characteristic of osteoporosis. The complexity of this method stems from the requirement for high-quality 3D reconstructions of the murine bones. However, respiratory motion and muscle relaxation lead to inconsistencies in the projection data which result in artifacts in uncompensated reconstructions. Motion compensation using epipolar consistency conditions (ECC) has previously shown good performance in clinical CT settings. Here, we explore whether such algorithms are suitable for correcting motion-corrupted XRM data. Different rigid motion patterns are simulated and the quality of the motion-compensated reconstructions is assessed. The method is able to restore microscopic features for out-of-plane motion, but artifacts remain for more realistic motion patterns including all six degrees of freedom of rigid motion. Therefore, ECC is valuable for the initial alignment of the projection data followed by further fine-tuning of motion parameters using a reconstruction-based method.

Authors with CRIS profile

Involved external institutions

Fraunhofer-Institut für Keramische Technologien und Systeme (IKTS) Germany (DE)

How to cite

APA:

Thies, M., Wagner, F., Gu, M., Mei, S., Huang, Y., Pechmann, S.,... Maier, A. (2024). Exploring Epipolar Consistency Conditions for Rigid Motion Compensation in In-vivo X-ray Microscopy. In Andreas Maier, Thomas M. Deserno, Heinz Handels, Klaus Maier-Hein, Christoph Palm, Thomas Tolxdorff (Eds.), Informatik aktuell (pp. 211-216). Erlangen, DEU: Springer Science and Business Media Deutschland GmbH.

MLA:

Thies, Mareike, et al. "Exploring Epipolar Consistency Conditions for Rigid Motion Compensation in In-vivo X-ray Microscopy." Proceedings of the German Conference on Medical Image Computing, BVM 2024, Erlangen, DEU Ed. Andreas Maier, Thomas M. Deserno, Heinz Handels, Klaus Maier-Hein, Christoph Palm, Thomas Tolxdorff, Springer Science and Business Media Deutschland GmbH, 2024. 211-216.

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