Comparison of microstructure, sintering behavior, and biological response of sol-gel and melt-derived 13–93 bioactive glass scaffolds

Nawaz Q, de Pablos-Martín A, Contreras Jaimes AT, Scheffler F, Wagner T, Brauer DS, Boccaccini AR (2023)

Publication Type: Journal article

Publication year: 2023

Journal

Open Ceramics Elsevier

Book Volume: 15

Article Number: 100407

DOI: 10.1016/j.oceram.2023.100407

Abstract

In this study, 13–93 bioactive glass (BG) powders were obtained through the traditional melt-quenching and sol-gel approaches and were used to fabricate scaffolds using the well-known foam replica technique. A comparative analysis of scaffolds prepared using sol-gel and melt-derived powders was carried out. The microstructure of scaffolds was examined by scanning electron microscopy (SEM) and X-ray computed tomography. The shrinkage behavior of the scaffold structure during sintering was investigated using heating microscopy (HM). The bioactivity results indicated the formation of a hydroxyapatite layer on the surface of both scaffolds after immersion in simulated body fluid (SBF) for 7 days. In vitro cell viability results revealed that both scaffolds are cytocompatible with MG-63 cells (osteoblast-like cell line). The findings indicate that sol-gel glass-derived 13–93 scaffolds exhibited similar characteristics to the well-known melt-derived 13–93 scaffolds. Moreover, the low-temperature processing and high purity associated with the sol-gel approach suggest that sol-gel derived 13–93 BG powder is attractive for fabricating high-quality scaffolds.

Authors with CRIS profile

Qaisar Nawaz Lehrstuhl für Werkstoffwissenschaften (Biomaterialien) Aldo Boccaccini Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)

Involved external institutions

Friedrich-Schiller-Universität Jena DE Germany (DE) Fraunhofer-Institut für Mikrostruktur von Werkstoffen und Systemen IMWS DE Germany (DE)

How to cite

APA:

Nawaz, Q., de Pablos-Martín, A., Contreras Jaimes, A.T., Scheffler, F., Wagner, T., Brauer, D.S., & Boccaccini, A.R. (2023). Comparison of microstructure, sintering behavior, and biological response of sol-gel and melt-derived 13–93 bioactive glass scaffolds. Open Ceramics, 15. https://doi.org/10.1016/j.oceram.2023.100407

MLA:

Nawaz, Qaisar, et al. "Comparison of microstructure, sintering behavior, and biological response of sol-gel and melt-derived 13–93 bioactive glass scaffolds." Open Ceramics 15 (2023).

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