Towards a Synthetic Tissue Model of the Lower Urinary Tract

Preis A, Merkl C, Miralles P, Heer S, Benke E, Reitelshöfer S, Martin S, Rieker R, Franke J (2023)

Publication Type: Conference contribution

Publication year: 2023

Pages Range: 190-197

Conference Proceedings Title: Proceedings of the 16th International Joint Conference on Biomedical Engineering Systems and Technologies BIOSTEC - (Volume 1)

Event location: Lisbon PT

ISBN: 978-989-758-631-6

DOI: 10.5220/0011780500003414

Abstract

The development of medical devices often depends on in vivo studies to validate the proper functioning of the products. These trials provide ethical as well as economic challenges, which can be partially addressed by the usage of realistic synthetic tissue models that replicate human anatomy and the corresponding properties of the biological tissue. In this work, a silicone-based model with a fiber structure and a PVA-based model that exhibits fabrication-induced anisotropy are presented in the special context of the lower urinary tract. The analysis of the materials in the uniaxial tensile test shows the anisotropic and viscoelastic properties of the materials. Furthermore, the anatomical model of the lower urinary tract shows expected deformation in simulation as well as in the real silicone model. Additionally, a suitable artificial urine according to ISO 20696 is shown for use with the model. First experiments to change the pH of the artificial urine are successfully conducted.

Authors with CRIS profile

Alexander Preis Lehrstuhl für Fertigungsautomatisierung und Produktionssystematik Christina Merkl Lehrstuhl für Fertigungsautomatisierung und Produktionssystematik Elisabeth Benke Lehrstuhl für Fertigungsautomatisierung und Produktionssystematik Sebastian Reitelshöfer Lehrstuhl für Fertigungsautomatisierung und Produktionssystematik Sina Martin Lehrstuhl für Fertigungsautomatisierung und Produktionssystematik Ralf Rieker Institute of Pathology Jörg Franke Lehrstuhl für Fertigungsautomatisierung und Produktionssystematik

How to cite

APA:

Preis, A., Merkl, C., Miralles, P., Heer, S., Benke, E., Reitelshöfer, S.,... Franke, J. (2023). Towards a Synthetic Tissue Model of the Lower Urinary Tract. In Proceedings of the 16th International Joint Conference on Biomedical Engineering Systems and Technologies BIOSTEC - (Volume 1) (pp. 190-197). Lisbon, PT.

MLA:

Preis, Alexander, et al. "Towards a Synthetic Tissue Model of the Lower Urinary Tract." Proceedings of the 16th International Joint Conference on Biomedical Engineering Systems and Technologies, Lisbon 2023. 190-197.

BibTeX: Download