C orynebacterium guaraldiae sp. nov.: a new species of Corynebacterium from human infections
de Oliveira Sant’Anna L, dos Santos LS, Araújo MRB, da Rocha DJPG, Ramos JN, Baio PVP, Del Peloso PF, da Costa Ferreira Leite C, Stavracakis Peixoto R, Almuzara M, Vay C, Barberis C, Sangal V, Burkovski A, Aguiar ERGR, Mattos-Guaraldi AL, Pacheco LGC, Vieira VV (2023)
Publication Type: Journal article
Publication year: 2023
Journal
DOI: 10.1007/s42770-023-00938-y
Abstract
Non-diphtheria Corynebacterium species (NDC) belonging to the human skin and mucosa microbiota are frequently neglected as contaminants. However, reports of human infections by Corynebacterium spp. have increased considerably in recent years. In this study, a group of six NDC isolates of urine (n = 5) and sebaceous cyst (n = 1) from two South American countries were identified at genus level or misidentified based on API® Coryne and genetic/molecular analyses. The 16S rRNA (99.09–99.56%) and rpoB (96.18–97.14%) gene sequence similarities of the isolates were higher when compared with Corynebacterium aurimucosum DSM 44532 T. Multilocus sequence analysis (MLSA) indicated that these six NDC isolates compose a distinctive phylogenetic clade. Genome-based taxonomic analysis with the whole-genome sequences was able to separate these six isolates from other known Corynebacterium type strains. Average nucleotide identity (ANI), average amino acid identity (AAI), and digital DNA–DNA hybridization (dDDH) values between closely related type strains and the six isolates were considerably lower than the currently recommended threshold values for species circumscription. Phylogenetic and genomic taxonomy analyses indicated these microorganisms as a novel Corynebacterium species, for which we formally propose the name Corynebacterium guaraldiae sp. nov. with isolate 13T (= CBAS 827T = CCBH 35012T) as type strain.
Authors with CRIS profile
Renata Stavracakis Peixoto
Professur für Mikrobiologie
Andreas Burkovski
Professur für Mikrobiologie
Involved external institutions
Northumbria University
United Kingdom (GB)
Universidad de Buenos Aires (UBA) / University of Buenos Aires
Argentina (AR)
Rio de Janeiro State University / Universidade do Estado do Rio de Janeiro (UERJ)
Brazil (BR)
State University of Santa Cruz / Universidade Estadual de Santa Cruz (UESC)
Brazil (BR)
Universidade Federal da Bahia
Brazil (BR)
Hermes Pardini Institute / Instituto Hermes Pardini S.A.
Brazil (BR)
Oswaldo Cruz Foundation / Fundação Oswaldo Cruz (FIOCRUZ)
Brazil (BR)
United Kingdom (GB)
Universidad de Buenos Aires (UBA) / University of Buenos Aires
Argentina (AR)
Rio de Janeiro State University / Universidade do Estado do Rio de Janeiro (UERJ)
Brazil (BR)
State University of Santa Cruz / Universidade Estadual de Santa Cruz (UESC)
Brazil (BR)
Universidade Federal da Bahia
Brazil (BR)
Hermes Pardini Institute / Instituto Hermes Pardini S.A.
Brazil (BR)
Oswaldo Cruz Foundation / Fundação Oswaldo Cruz (FIOCRUZ)
Brazil (BR)
How to cite
APA:
de Oliveira Sant’Anna, L., dos Santos, L.S., Araújo, M.R.B., da Rocha, D.J.P.G., Ramos, J.N., Baio, P.V.P.,... Vieira, V.V. (2023). C orynebacterium guaraldiae sp. nov.: a new species of Corynebacterium from human infections. Brazilian Journal of Microbiology. https://dx.doi.org/10.1007/s42770-023-00938-y
MLA:
de Oliveira Sant’Anna, Lincoln, et al. "C orynebacterium guaraldiae sp. nov.: a new species of Corynebacterium from human infections." Brazilian Journal of Microbiology (2023).
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