Quantitative protein sensing with germanium THz-antennas manufactured using CMOS processes
Hardt E, Chavarin CA, Gruessing S, Flesch J, Skibitzki O, Spirito D, Vita GM, Simone GD, Masi AD, You C, Witzigmann B, Piehler J, Capellini G (2022)
Publication Type: Journal article
Publication year: 2022
Journal
Book Volume: 30
Pages Range: 40265-40276
Journal Issue: 22
DOI: 10.1364/OE.469496
Abstract
The development of a CMOS manufactured THz sensing platform could enable the integration of state-of-the-art sensing principles with the mixed signal electronics ecosystem in small footprint, low-cost devices. To this aim, in this work we demonstrate a label-free protein sensing platform using highly doped germanium plasmonic antennas realized on Si and SOI substrates and operating in the THz range of the electromagnetic spectrum. The antenna response to different concentrations of BSA shows in both cases a linear response with saturation above 20 mg/mL. Ge antennas on SOI substrates feature a two-fold sensitivity as compared to conventional Si substrates, reaching a value of 6 GHz/(mg/mL), which is four-fold what reported using metal-based metamaterials. We believe that this result could pave the way to a low-cost lab-on-a-chip biosensing platform.
Authors with CRIS profile
Involved external institutions
Università degli Studi Roma Tre
Italy (IT)
Universität Osnabrück
Germany (DE)
Leibniz-Institut für innovative Mikroelektronik / IHP GmbH - Innovations for High Performance Microelectronics
Germany (DE)
Universität Kassel
Germany (DE)
Italy (IT)
Universität Osnabrück
Germany (DE)
Leibniz-Institut für innovative Mikroelektronik / IHP GmbH - Innovations for High Performance Microelectronics
Germany (DE)
Universität Kassel
Germany (DE)
How to cite
APA:
Hardt, E., Chavarin, C.A., Gruessing, S., Flesch, J., Skibitzki, O., Spirito, D.,... Capellini, G. (2022). Quantitative protein sensing with germanium THz-antennas manufactured using CMOS processes. Optics Express, 30(22), 40265-40276. https://doi.org/10.1364/OE.469496
MLA:
Hardt, Elena, et al. "Quantitative protein sensing with germanium THz-antennas manufactured using CMOS processes." Optics Express 30.22 (2022): 40265-40276.
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