CODE-EHR best practice framework for the use of structured electronic healthcare records in clinical research

Kotecha D, Asselbergs FW, Achenbach S, Anker SD, Atar D, Baigent C, Banerjee A, Beger B, Brobert G, Casadei B, Ceccarelli C, Cowie MR, Crea F, Cronin M, Denaxas S, Derix A, Fitzsimons D, Fredriksson M, Gale CP, Gkoutos G, Goettsch W, Hemingway H, Ingvar M, Jonas A, Kazmierski R, Logstrup S, Lumbers RT, Luescher TF, Mcgreavy P, Pina IL, Roessig L, Steinbeisser C, Sundgren M, Tyl B, Van Thiel G, Van Bochove K, Vardas PE, Villanueva T, Vrana M, Weber W, Weidinger F, Windecker S, Wood A, Grobbe DE (2022)

Publication Type: Journal article

Publication year: 2022

Journal

DOI: 10.1093/eurheartj/ehac426

Abstract

Big data is central to new developments in global clinical science aiming to improve the lives of patients. Technological advances have led to the routine use of structured electronic healthcare records with the potential to address key gaps in clinical evidence. The covid-19 pandemic has demonstrated the potential of big data and related analytics, but also important pitfalls. Verification, validation, and data privacy, as well as the social mandate to undertake research are key challenges. The European Society of Cardiology and the BigData@Heart consortium have brought together a range of international stakeholders, including patient representatives, clinicians, scientists, regulators, journal editors and industry. We propose the CODE-EHR Minimum Standards Framework as a means to improve the design of studies, enhance transparency and develop a roadmap towards more robust and effective utilisation of healthcare data for research purposes.

Authors with CRIS profile

Involved external institutions

University of Birmingham United Kingdom (GB) Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK e.V.) Germany (DE) University of Zurich / Universität Zürich (UZH) Switzerland (CH) British Medical Association (BMA) United Kingdom (GB) Royal Brompton Hospital United Kingdom (GB) University College London (UCL) United Kingdom (GB) University of Oxford United Kingdom (GB) Karolinska Institute Sweden (SE) University Hospitals Birmingham NHS Foundation Trust United Kingdom (GB) University of Leeds United Kingdom (GB) Hellenic Healthcare Group Greece (GR) Bayer AG Germany (DE) The National Institute for Health and Care Excellence United Kingdom (GB) Catholic University of the Sacred Heart / Università Cattolica del Sacro Cuore Italy (IT) AstraZeneca UK Limited United Kingdom (GB) Food and Drug Administration (FDA / USFDA) United States (USA) (US) Inselspital, Universitätsspital Bern Switzerland (CH) Vifor Pharma AG Switzerland (CH) University Medical Centre Utrecht (UMC Utrecht) Netherlands (NL) European Heart Network (EHN) Belgium (BE) European Society of Cardiology Belgium (BE) Central Michigan University United States (USA) (US) National Health Care Institute Netherlands (NL) Queen's University United Kingdom (GB) Krankenanstalt Rudolfstiftung Austria (AT) University of Cambridge United Kingdom (GB) Universiteit Utrecht (UU) / Utrecht University Netherlands (NL) The Hyve Netherlands (NL) Bayer AB Sweden (SE) Oslo University Hospital / Oslo Universitetssykehus Rikshospitalet Norway (NO) Laboratoires Servier France (FR)

How to cite

APA:

Kotecha, D., Asselbergs, F.W., Achenbach, S., Anker, S.D., Atar, D., Baigent, C.,... Grobbe, D.E. (2022). CODE-EHR best practice framework for the use of structured electronic healthcare records in clinical research. European Heart Journal. https://dx.doi.org/10.1093/eurheartj/ehac426

MLA:

Kotecha, Dipak, et al. "CODE-EHR best practice framework for the use of structured electronic healthcare records in clinical research." European Heart Journal (2022).

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