Fibrous protein-based biomaterials (silk, keratin, elastin, and resilin proteins) for tissue regeneration and repair

Costa F, Marques da Silva Lourenco RdJ, Boccaccini AR (2018)

Publication Type: Book chapter / Article in edited volumes

Publication year: 2018

Publisher: Elsevier Inc.

Edited Volumes: Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair

Pages Range: 175-204

ISBN: 9780081008522

DOI: 10.1016/B978-0-08-100803-4.00007-3

Abstract

Tissue scaffolds are essential in tissue engineering approaches as they provide a tissue-mimicking environment for cells, with the aim to promote cell proliferation, cell differentiation, and tissue regeneration. To mimic better the microenvironment of native tissues, numerous techniques, and biomaterials have emerged in recent years. Among them, hydrogels formed from self-assembled biopolymer networks are particularly interesting. This chapter reviews the fabrication and use of fibrous protein-based hydrogels, with an emphasis on silk, keratin, elastin, and resilin proteins. Hydrogels formed by these proteins show structural, chemical, and mechanical similarities with the extracellular matrix of human tissues, typically exhibiting biological compatibility, and they can trigger specific cellular responses. In addition, these hydrogels can be degraded in the body by proteolytic enzymes. For these reasons, fibrous protein hydrogels are versatile materials for tissue engineering.

Authors with CRIS profile

Raquel de Jesus Marques da Silva Lourenco Lehrstuhl für Werkstoffwissenschaften (Biomaterialien) Aldo Boccaccini Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)

Involved external institutions

Universidade do Porto PT Portugal (PT)

How to cite

APA:

Costa, F., Marques da Silva Lourenco, R.d.J., & Boccaccini, A.R. (2018). Fibrous protein-based biomaterials (silk, keratin, elastin, and resilin proteins) for tissue regeneration and repair. In Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair. (pp. 175-204). Elsevier Inc..

MLA:

Costa, F., Raquel de Jesus Marques da Silva Lourenco, and Aldo R. Boccaccini. "Fibrous protein-based biomaterials (silk, keratin, elastin, and resilin proteins) for tissue regeneration and repair." Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair. Elsevier Inc., 2018. 175-204.

BibTeX: Download