Outcomes addressed in randomized controlled lifestyle intervention trials in community-dwelling older people with (sarcopenic) obesity—An evidence map

Galicia Ernst I, Torbahn G, Schwingshackl L, Knuettel H, Kob R, Kemmler W, Sieber C, Batsis JA, Villareal DT, Stroebele-Benschop N, Visser M, Volkert D, Kießwetter E, Schöne D (2022)

Publication Type: Journal article, Review article

Publication year: 2022

Journal

Obesity Reviews Wiley-Blackwell

DOI: 10.1111/obr.13497

Abstract

Obesity and sarcopenic obesity (SO) are characterized by excess body fat with or without low muscle mass affecting bio-psycho-social health, functioning, and subsequently quality of life in older adults. We mapped outcomes addressed in randomized controlled trials (RCTs) on lifestyle interventions in community-dwelling older people with (sarcopenic) obesity. Systematic searches in Medline, Embase, Cochrane Central, CINAHL, PsycInfo, Web of Science were conducted. Two reviewers independently performed screening and extracted data on outcomes, outcome domains, assessment methods, units, and measurement time. A bubble chart and heat maps were generated to visually display results. Fifty-four RCTs (7 in SO) reporting 464 outcomes in the outcome domains: physical function (n = 42), body composition/anthropometry (n = 120), biomarkers (n = 190), physiological (n = 30), psychological (n = 47), quality of life (n = 14), pain (n = 4), sleep (n = 2), medications (n = 3), and risk of adverse health events (n = 5) were included. Heterogeneity in terms of outcome definition, assessment methods, measurement units, and measurement times was found. Psychological and quality of life domains were investigated in a minority of studies. There is almost no information beyond 52 weeks. This evidence map is the first step of a harmonization process to improve comparability of RCTs in older people with (sarcopenic) obesity and facilitate the derivation of evidence-based clinical decisions.

Authors with CRIS profile

Isabel Galicia Ernst Lehrstuhl für Innere Medizin (Geriatrie) Gabriel Torbahn Lehrstuhl für Innere Medizin (Geriatrie) Robert Kob Professur für Innere Medizin - Geriatrie Wolfgang Kemmler Lehrstuhl für Medizinische Physik und Mikrogewebetechnik Cornel Sieber Lehrstuhl für Innere Medizin (Geriatrie) Dorothee Volkert Professur für Klinische Ernährung im Alter Eva Kießwetter Professur für Klinische Ernährung im Alter Daniel Schöne Lehrstuhl für Medizinische Physik und Mikrogewebetechnik

Involved external institutions

University of North Carolina at Chapel Hill US United States (USA) (US) Vrije Universiteit Amsterdam (VU) / University Amsterdam NL Netherlands (NL) Universität Regensburg DE Germany (DE) Houston Texas Medical Center US United States (USA) (US) Universität Hohenheim DE Germany (DE) Albert-Ludwigs-Universität Freiburg DE Germany (DE)

How to cite

APA:

Galicia Ernst, I., Torbahn, G., Schwingshackl, L., Knuettel, H., Kob, R., Kemmler, W.,... Schöne, D. (2022). Outcomes addressed in randomized controlled lifestyle intervention trials in community-dwelling older people with (sarcopenic) obesity—An evidence map. Obesity Reviews. https://dx.doi.org/10.1111/obr.13497

MLA:

Galicia Ernst, Isabel, et al. "Outcomes addressed in randomized controlled lifestyle intervention trials in community-dwelling older people with (sarcopenic) obesity—An evidence map." Obesity Reviews (2022).

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