COVID-19 effects on the kidney.

Amann KU, Boor P, Wiech T, Singh J, Vonbrunn E, Knöll A, Hermann M, Büttner-Herold M, Daniel C, Hartmann A (2021)


Publication Type: Journal article, Review article

Publication year: 2021

Journal

Book Volume: 42

Pages Range: 76-80

Journal Issue: Suppl 1

DOI: 10.1007/s00292-020-00900-x

Abstract

Apart from pulmonary disease, acute kidney injury (AKI) is one of the most frequent and most severe organ complications in severe coronavirus disease 2019 (COVID-19). The SARS-CoV‑2 virus has been detected in renal tissue. Patients with chronic kidney disease (CKD) before and on dialysis and specifically renal transplant patients represent a particularly vulnerable population. The increasing number of COVID-19 infected patients with renal involvement led to an evolving interest in the analysis of its pathophysiology, morphology and modes of virus detection in the kidney. Meanwhile, there are ample data from several autopsy and kidney biopsy studies that differ in the quantity of cases as well as in their quality. While the detection of SARS-CoV‑2 RNA in the kidney leads to reproducible results, the use of electron microscopy for visualisation of the virus is difficult and currently critically discussed due to various artefacts. The exact contribution of indirect or direct effects on the kidney in COVID-19 are not yet known and are currently the focus of intensive research.

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How to cite

APA:

Amann, K.U., Boor, P., Wiech, T., Singh, J., Vonbrunn, E., Knöll, A.,... Hartmann, A. (2021). COVID-19 effects on the kidney. Pathologe, 42(Suppl 1), 76-80. https://dx.doi.org/10.1007/s00292-020-00900-x

MLA:

Amann, Kerstin Ute, et al. "COVID-19 effects on the kidney." Pathologe 42.Suppl 1 (2021): 76-80.

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