Protein-Based Hydrogels: Promising Materials for Tissue Engineering

Davari N, Bakhtiary N, Khajehmohammadi M, Sarkari S, Tolabi H, Ghorbani F, Ghalandari B (2022)

Publication Type: Journal article

Publication year: 2022

Journal

Polymers MDPI

Book Volume: 14

Journal Issue: 5

DOI: 10.3390/polym14050986

Abstract

The successful design of a hydrogel for tissue engineering requires a profound understanding of its constituents' structural and molecular properties, as well as the proper selection of components. If the engineered processes are in line with the procedures that natural materials undergo to achieve the best network structure necessary for the formation of the hydrogel with desired properties, the failure rate of tissue engineering projects will be significantly reduced. In this review, we examine the behavior of proteins as an essential and effective component of hydrogels, and describe the factors that can enhance the protein-based hydrogels' structure. Furthermore, we outline the fabrication route of protein-based hydrogels from protein microstructure and the selection of appropriate materials according to recent research to growth factors, crucial members of the protein family, and their delivery approaches. Finally, the unmet needs and current challenges in developing the ideal biomaterials for protein-based hydrogels are discussed, and emerging strategies in this area are highlighted.

Authors with CRIS profile

Farnaz Ghorbani Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)

Involved external institutions

University of Tehran IR Iran, Islamic Republic of (IR) Iran University of Medical Sciences (IUMS) / دانشگاه علوم پزشکی ایران IR Iran, Islamic Republic of (IR) Yazd University / دانشگاه یزد IR Iran, Islamic Republic of (IR) Islamic Azad University (IAU) / دانشگاه آزاد اسلامی‎‎ IR Iran, Islamic Republic of (IR) Amirkabir University of Technology (AUT) / دانشگاه صنعتی امیرکبیر IR Iran, Islamic Republic of (IR) Shanghai Jiao Tong University / 上海交通大学 CN China (CN)

How to cite

APA:

Davari, N., Bakhtiary, N., Khajehmohammadi, M., Sarkari, S., Tolabi, H., Ghorbani, F., & Ghalandari, B. (2022). Protein-Based Hydrogels: Promising Materials for Tissue Engineering. Polymers, 14(5). https://dx.doi.org/10.3390/polym14050986

MLA:

Davari, Niyousha, et al. "Protein-Based Hydrogels: Promising Materials for Tissue Engineering." Polymers 14.5 (2022).

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