Substrate-integrated microfluidics for sensitive biosensing with complementary THz metamaterials in water

Weisenstein C, Richter M, Wigger AK, Boßerhoff AK, Haring Bolivar P (2022)

Publication Type: Journal article

Publication year: 2022

Journal

Applied Physics Letters American Institute of Physics (AIP)

Book Volume: 120

Journal Issue: 5

DOI: 10.1063/5.0076379

Abstract

Metamaterials can be utilized for a variety of applications and have emerged as a valuable tool in THz technologies. Used as THz biosensors, metasurfaces can significantly improve the sensitivity in the detection of biomolecules, but the high THz absorption of water represents a major challenge for the realization of a sensor for measurements in liquids. In this article, we propose an approach where the resonance feature of complementary asymmetric split ring resonators (CASRR) is maintained even for measurements in water, allowing highly sensitive detection of biomolecules in strongly absorbing liquids. This is enabled by the introduction of substrate-integrated microfluidics, which are shown to have a minimal effect on the transmission properties of the metamaterial. Due to this approach, the metamaterial structure design is independent from the microfluidic channels. Our simulations also show that the sensitivity of CASRR changes only marginally for lossless and highly absorbing materials. At the same time, the presented concept is easy to fabricate by standard lithography methods and can be applied to other metamaterial structures as well. (C) 2022 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

Authors with CRIS profile

Anja Katrin Boßerhoff Lehrstuhl für Biochemie und Molekulare Medizin

Involved external institutions

Universität Siegen DE Germany (DE)

How to cite

APA:

Weisenstein, C., Richter, M., Wigger, A.K., Boßerhoff, A.K., & Haring Bolivar, P. (2022). Substrate-integrated microfluidics for sensitive biosensing with complementary THz metamaterials in water. Applied Physics Letters, 120(5). https://dx.doi.org/10.1063/5.0076379

MLA:

Weisenstein, Christian, et al. "Substrate-integrated microfluidics for sensitive biosensing with complementary THz metamaterials in water." Applied Physics Letters 120.5 (2022).

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